Baad Vanessa M A, Bezerra Louise R, de Holanda Narriane C P, Dos Santos Ana C O, da Silva Amanda A M, Bandeira Francisco, Cavalcante Taisy C F
Faculty of Medical Sciences, Post-Graduation in Health Sciences, University of Pernambuco, Recife, Brazil.
Department of Endocrinology, Federal University of Paraiba, João Pessoa, Brazil.
Obes Surg. 2022 Dec;32(12):3830-3838. doi: 10.1007/s11695-022-06335-y. Epub 2022 Oct 28.
Evaluate the differences between surgical techniques in the modifications of body composition and the interference in skeletal muscle health, risk of sarcopenia, and reduced physical performance.
This is a cross-sectional prospective study. A total of 71 patients, who underwent sleeve gastrectomy (SG) or underwent Roux-en-Y gastric bypass (RYGB). Both groups underwent anthropometric, laboratory analysis, body composition assessment, presence of sarcopenia, and physical performance tests.
The study found a higher percentage of weight loss and lower BMI in RYGB compared to SG. The other assessments of sarcopenia and physical performance showed similarity between the surgical models. Baumgartner index (7.9 kg/m vs. 7.3 kg/m), FNIH (9.0 vs. 3.0), handgrip strength (27.3 kg vs. 25.2 kg), and SPPB (9.5 vs. 9.3). Leptin in the general SG group was higher than in RYGB (14.2 ng/ml vs. 8.0 ng/ml).
RYGB and SG have a similar presence of sarcopenia and physical performance. However, SG allows greater preservation of bone and muscle mass and is associated with higher values of leptin, which may represent protection from long-term postoperative complications.
评估手术技术在身体成分改变、对骨骼肌健康的影响、肌肉减少症风险及身体机能下降方面的差异。
这是一项横断面前瞻性研究。共有71例患者，分别接受了袖状胃切除术（SG）或Roux-en-Y胃旁路术（RYGB）。两组患者均接受了人体测量、实验室分析、身体成分评估、肌肉减少症检查及身体机能测试。
研究发现，与SG组相比，RYGB组的体重减轻百分比更高，体重指数更低。其他关于肌肉减少症和身体机能的评估显示，两种手术模式之间存在相似性。鲍姆加特纳指数（7.9千克/米对7.3千克/米）、美国国立卫生研究院肌肉减少症项目标准（9.0对3.0）、握力（27.3千克对25.2千克）和简易体能状况量表（9.5对9.3）。一般SG组的瘦素水平高于RYGB组（14.2纳克/毫升对8.0纳克/毫升）。
RYGB和SG出现肌肉减少症和身体机能下降的情况相似。然而，SG能更好地保留骨骼和肌肉质量，且与更高的瘦素值相关，这可能意味着对术后长期并发症有保护作用。
