文献检索文档翻译深度研究
Suppr Zotero 插件Zotero 插件
邀请有礼套餐&价格历史记录

新学期，新优惠

限时优惠:9月1日-9月22日

30天高级会员仅需29元

1天体验卡首发特惠仅需5.99元

了解详情
不再提醒
插件&应用
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
高级版
套餐订阅购买积分包
AI 工具
文献检索文档翻译深度研究
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2025

Stimuli-responsive linkers and their application in molecular imaging.

作者信息

Wang Jing, Liu Meng, Zhang Xinyue, Wang Xinning, Xiong Menghua, Luo Dong

机构信息

School of Biomedical Sciences and Engineering South China University of Technology Guangzhou P. R. China.

Department of Biomedical Engineering Case Western Reserve University Cleveland Ohio USA.

出版信息

Exploration (Beijing). 2024 Jan 18;4(4):20230027. doi: 10.1002/EXP.20230027. eCollection 2024 Aug.

DOI:10.1002/EXP.20230027
PMID:39175888
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11335469/
Abstract

Molecular imaging is a non-invasive imaging method that is widely used for visualization and detection of biological events at cellular or molecular levels. Stimuli-responsive linkers that can be selectively cleaved by specific biomarkers at desired sites to release or activate imaging agents are appealing tools to improve the specificity, sensitivity, and efficacy of molecular imaging. This review summarizes the recent advances of stimuli-responsive linkers and their application in molecular imaging, highlighting the potential of these linkers in the design of activatable molecular imaging probes. It is hoped that this review could inspire more research interests in the development of responsive linkers and associated imaging applications.

摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/da8fc82d138d/EXP2-4-20230027-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/03f6056260dc/EXP2-4-20230027-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/734d812c551e/EXP2-4-20230027-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/7d58c98a90ef/EXP2-4-20230027-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/09f8e965c040/EXP2-4-20230027-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/880bb2633561/EXP2-4-20230027-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/8e0c29958ab1/EXP2-4-20230027-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/403002a4d1a1/EXP2-4-20230027-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/da8fc82d138d/EXP2-4-20230027-g008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/03f6056260dc/EXP2-4-20230027-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/734d812c551e/EXP2-4-20230027-g013.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/7d58c98a90ef/EXP2-4-20230027-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/09f8e965c040/EXP2-4-20230027-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/880bb2633561/EXP2-4-20230027-g011.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/8e0c29958ab1/EXP2-4-20230027-g010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/403002a4d1a1/EXP2-4-20230027-g007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6ac/11335469/da8fc82d138d/EXP2-4-20230027-g008.jpg

相似文献

[1]
Stimuli-responsive linkers and their application in molecular imaging.

Exploration (Beijing). 2024-1-18

[2]
Activatable dual-functional molecular agents for imaging-guided cancer therapy.

Adv Drug Deliv Rev. 2023-4

[3]
A preliminary study for the development of cleavable linkers using activatable fluorescent probes targeting leucine aminopeptidase.

Analyst. 2022-11-21

[4]
[Reactive oxygen species stimuli-responsive nanocarriers].

Se Pu. 2021-2

[5]
Temperature switchable linkers suitable for triggered drug release in cancer thermo-chemotherapy.

Int J Pharm. 2024-12-5

[6]
Chemical Design of Activatable Photoacoustic Probes for Precise Biomedical Applications.

Chem Rev. 2022-3-23

[7]
Polymeric agents for activatable fluorescence, self-luminescence and photoacoustic imaging.

Biosens Bioelectron. 2022-8-15

[8]
Light-activatable dual prodrug polymer nanoparticle for precise synergistic chemotherapy guided by drug-mediated computed tomography imaging.

Acta Biomater. 2019-5-22

[9]
Nanomaterial-based activatable imaging probes: from design to biological applications.

Chem Soc Rev. 2015-11-7

[10]
Endogenous stimuli-responsive linkers in nanoliposomal systems for cancer drug targeting.

Int J Pharm. 2019-11-6

引用本文的文献

[1]
A dual-enzyme activated fluorescent probe for precise identification of tumor senescence.

Chem Sci. 2025-3-11

[2]
Photothermal sensitive nanocomposite hydrogel for infectious bone defects.

Bone Res. 2025-2-14

本文引用的文献

[1]
Recent development of pH-responsive theranostic nanoplatforms for magnetic resonance imaging-guided cancer therapy.

Exploration (Beijing). 2023-3-30

[2]
Stimuli-responsive crosslinked nanomedicine for cancer treatment.

Exploration (Beijing). 2022-4-21

[3]
Organic fluorescent nanoprobes with NIR-IIb characteristics for deep learning.

Exploration (Beijing). 2022-2-19

[4]
Ultrasound-controlled drug release and drug activation for cancer therapy.

Exploration (Beijing). 2021-12-28

[5]
Dual-locked spectroscopic probes for sensing and therapy.

Nat Rev Chem. 2021-6

[6]
Molecular Engineering of Self-Immolative Bioresponsive MR Probes.

J Am Chem Soc. 2023-5-10

[7]
Intracellular Construction of Cathepsin B-Guided Gadolinium Nanoparticles for Enhanced T -Weighted MR Tumor Imaging.

Small. 2023-7

[8]
Highly selective chemosensor for the sensitive detection of Hg in aqueous media and its cell imaging application.

Spectrochim Acta A Mol Biomol Spectrosc. 2023-8-5

[9]
Activatable fluorescent probes for real-time imaging-guided tumor therapy.

Adv Drug Deliv Rev. 2023-5

[10]
Dual-Parameter Recognition-Directed Design of the Activatable Fluorescence Probe for Precise Imaging of Cellular Senescence.

Anal Chem. 2023-2-28

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

推荐工具

医学文档翻译智能文献检索