日本新生儿疱疹感染早期诊断面临的挑战。
Challenges for early diagnosis of neonatal herpes infection in Japan.
作者信息
Kojima Junya, Suzuki Shunji, Hoshi Shin-Ichi, Sekizawa Akihiko, Sagara Yoko, Matsuda Hideo, Ishiwata Isamu, Kitamura Tadaichi
机构信息
Division of Maternal and Child Health, Japan Association of Obstetricians and Gynecologists, Tokyo, Japan.
Japanese Foundation for Sexual Health Medicine, Tokyo, Japan.
出版信息
Front Reprod Health. 2024 Aug 8;6:1393509. doi: 10.3389/frph.2024.1393509. eCollection 2024.
BACKGROUND
This study aimed to analyze the recent prevalence of neonatal herpes simplex virus infection, maternal symptoms in the presence of neonate who has herpes simplex virus infection, and mode of delivery in Japan.
METHODS
We requested 2.078 obstetrical facilities that are members of the Japan Association of Obstetricians and Gynecologists (JAOG) to provide information on neonatal herpes simplex virus infection involving deliveries at or after 22 weeks of gestation between 2020 and 2022. Of these, 1.371 (66.0%) facilities responded with information that could undergo statistical analysis.
RESULTS
There were 10 cases of neonatal herpes simplex virus infection, and the incidence of neonatal herpes simplex virus infection in Japan was about 1 in 1.4 × 10 live births. There were no characteristic maternal findings common to cases of neonatal herpes simplex virus infection.
CONCLUSION
The incidence of neonatal herpes simplex virus infection in Japan was low. We could not identify any characteristic maternal findings common to cases of neonatal herpes simplex virus infection.
背景
本研究旨在分析日本新生儿单纯疱疹病毒感染的近期患病率、新生儿感染单纯疱疹病毒时母亲的症状以及分娩方式。
方法
我们向日本妇产科医师协会（JAOG）的2078家产科机构请求提供2020年至2022年期间妊娠22周及以后分娩的新生儿单纯疱疹病毒感染信息。其中，1371家（66.0%）机构回复了可进行统计分析的信息。
结果
有10例新生儿单纯疱疹病毒感染病例，日本新生儿单纯疱疹病毒感染的发生率约为每1.4×10⁵例活产中有1例。新生儿单纯疱疹病毒感染病例没有共同的特征性母亲表现。
结论
日本新生儿单纯疱疹病毒感染的发生率较低。我们未能识别出新生儿单纯疱疹病毒感染病例共同的任何特征性母亲表现。
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