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原发性肺黏膜相关淋巴组织淋巴瘤伴广泛肺受累且无自身免疫和炎症背景:一例报告及文献复习

Primary pulmonary mucosa-associated lymphoid tissue lymphoma with extensive lung involvement and negative autoimmune and inflammatory background: A case report and literature review.

作者信息

Alabdulgader Abdulrahman I, Nabhan Arwa A, Althubaity Arwa M, Alsaid Abir H, Alsaif Hind S, Abualola Hossain A, Al-Mulhim Mohammed A, Alsayyah Ahmed A, Aldarweesh Mohammed I

机构信息

Department of Internal Medicine, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

Department of Radiology, College of Medicine, King Fahd Hospital of the University, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia.

出版信息

J Family Community Med. 2024 Jul-Sep;31(3):272-274. doi: 10.4103/jfcm.jfcm_365_23. Epub 2024 Jul 17.

DOI:10.4103/jfcm.jfcm_365_23
PMID:39176018
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11338395/
Abstract

Primary pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma is a very rare presentation of MALT lymphoma. The presence of a completely negative autoimmune and inflammatory background makes it a real challenge and very rare presentation (probably the second reported case in the literature). We report a case of primary pulmonary MALT lymphoma with negative autoimmune background, demonstrating as multifocal bulky variceal masses causing significant clinical symptoms.

摘要

原发性肺黏膜相关淋巴组织(MALT)淋巴瘤是MALT淋巴瘤一种非常罕见的表现形式。完全不存在自身免疫和炎症背景使其成为一项真正的挑战且极为罕见(可能是文献中报道的第二例)。我们报告一例原发性肺MALT淋巴瘤病例,其自身免疫背景呈阴性,表现为多灶性巨大静脉曲张样肿块,引发了显著的临床症状。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7561/11338395/92679ca9cdcd/JFCM-31-272-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7561/11338395/19b11766311c/JFCM-31-272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7561/11338395/92679ca9cdcd/JFCM-31-272-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7561/11338395/19b11766311c/JFCM-31-272-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7561/11338395/92679ca9cdcd/JFCM-31-272-g002.jpg

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本文引用的文献

1
Extranodal Marginal Zone Lymphoma: Pathogenesis, Diagnosis and Treatment.结外边缘区淋巴瘤:发病机制、诊断与治疗
Cancers (Basel). 2022 Mar 29;14(7):1742. doi: 10.3390/cancers14071742.
2
Primary Pulmonary B-Cell Lymphoma: A Review and Update.原发性肺B细胞淋巴瘤:综述与更新
Cancers (Basel). 2021 Jan 22;13(3):415. doi: 10.3390/cancers13030415.
3
Primary pulmonary MALT lymphoma presenting as non-resolving pneumonia.表现为迁延不愈肺炎的原发性肺黏膜相关淋巴组织淋巴瘤
Adv Respir Med. 2017;85(4):202-205. doi: 10.5603/ARM.2017.0033.
4
Pathways towards indolent B-cell lymphoma - Etiology and therapeutic strategies.惰性 B 细胞淋巴瘤的发生途径 - 病因和治疗策略。
Blood Rev. 2017 Nov;31(6):426-435. doi: 10.1016/j.blre.2017.08.002. Epub 2017 Aug 5.