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揭开中央牙本质生成性幽灵细胞瘤之谜——一例罕见病例报告及反复见解

Unravelling the mystery of the central dentinogenic ghost cell tumor- a rare case report and recurrent insights.

作者信息

Yadav Jagveer, Kamboj Mala, Devi Anju, Narwal Anjali, Chhikara Deepti, Saini Bhawna

机构信息

Department of Oral Maxillofacial Pathology and Microbiology, Post Graduate Institute of Dental Sciences, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India.

Department of Oral Maxillofacial Surgery, Post Graduate Institute of Dental Sciences, Pandit Bhagwat Dayal Sharma University of Health Sciences, Rohtak, Haryana, India.

出版信息

Autops Case Rep. 2024 Aug 15;14:e2024510. doi: 10.4322/acr.2024.510. eCollection 2024.

Abstract

Dentinogenic ghost cell tumor (DGCT) is a rare benign neoplasm form of calcifying odontogenic cyst (COC) characterized by ghost cells. Although benign, it presents an aggressive behavior. DGCT accounts for 2% to 14% of all COCs and less than 0.5% of all odontogenic tumors. It is a benign odontogenic tumor despite its local invasion and the likelihood of recurrence. To detect recurrence, central DGCT patients must be monitored long-term. We present the case of a 51-year-old male who reported pain in the right upper back tooth region. On examination, a soft to firm, bright red swelling was present in the buccal vestibule and gingival margin of the maxillary right first and second molar, which extended up to the palate. Histopathological analysis confirmed the diagnosis of a DGCT, which occurred in a previously treated calcifying odontogenic cyst. The case is reported here, along with a review of the literature update of such recurred instances in the past.

摘要

牙源性影细胞肿瘤(DGCT)是一种罕见的、以影细胞为特征的钙化牙源性囊肿(COC)的良性肿瘤形式。尽管它是良性的,但具有侵袭性行为。DGCT占所有COC的2%至14%,占所有牙源性肿瘤的不到0.5%。尽管它有局部侵袭和复发的可能性,但它是一种良性牙源性肿瘤。为了检测复发情况,必须对中心型DGCT患者进行长期监测。我们报告了一例51岁男性患者,他自述右上后牙区疼痛。检查发现,上颌右侧第一和第二磨牙的颊侧前庭和牙龈边缘有一个质地由软到硬的鲜红色肿胀,向上延伸至腭部。组织病理学分析证实诊断为DGCT,该肿瘤发生在先前治疗过的钙化牙源性囊肿中。本文报告了该病例,并对过去此类复发病例的文献更新进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d8d5/11340818/238f34f968dc/autopsy-14-e2024510-g01.jpg

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