Salma Ummey, Pushpalatha C, Sowmya S V, Augustine Dominic, Alamoudi Ahmed, Zidane Bassam, Albar Nassreen Hassan Mohammad, Bhandi Shilpa
Department of Pediatric and Preventive Dentistry, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India.
Department of Oral Pathology & Microbiology, Faculty of Dental Sciences, M.S. Ramaiah University of Applied Sciences, Bangalore, India.
Saudi Dent J. 2024 Aug;36(8):1093-1096. doi: 10.1016/j.sdentj.2024.05.006. Epub 2024 May 15.
Phytic acid (inositol hexaphosphate/IP6) is a versatile chemical that is abundant in nature and is required for a variety of biological processes. It is harnessed in a wide range of fields, including drug discovery, daily supplies, chemical industries, medicine, and dentistry. IP6 is becoming increasingly popular in dentistry, with promising results. Several properties, such as cariostatic ability, beneficial impact on enamel disintegration, and anti-plaque, anti-tartar, and dental adhesive-forming properties, have been investigated thus far. Due to many constraints in the literature, there was a point in time when IP6 received less attention, which impacted knowledge in this field. Nevertheless, the positive outcomes of the flourishing of IP6 have recently been reconsidered from a number of papers that have improved our understanding of its modes of action in the aforementioned applications. The role of phytic acid in refining the properties and manoeuvring of dental resources is being investigated in novel endeavors in treating diseases of pulp and tissues supporting tooth structure, but to show its novel therapeutic potential, more precisely calibrated clinical trials are needed. This review examines and discusses the various uses proposed in the literature, as well as the applications of IP6 in dentistry.
植酸（肌醇六磷酸/IP6）是一种用途广泛的化学物质，在自然界中含量丰富，是多种生物过程所必需的。它在广泛的领域中得到应用，包括药物研发、日常用品、化学工业、医学和牙科。IP6在牙科领域越来越受欢迎，取得了令人鼓舞的成果。迄今为止，已经对其多种特性进行了研究，如防龋能力、对牙釉质崩解的有益影响以及抗牙菌斑、抗牙石和形成牙科粘合剂的特性。由于文献中的诸多限制，IP6曾一度受到较少关注，这影响了该领域的知识积累。然而，最近一些论文重新审视了IP6蓬勃发展所带来的积极成果，这些论文增进了我们对其在上述应用中作用机制的理解。在治疗牙髓疾病和支持牙齿结构的组织疾病的新研究中，正在探讨植酸在改善牙科材料性能和操作方面的作用，但要展现其新的治疗潜力，还需要更精确校准的临床试验。这篇综述审视并讨论了文献中提出的各种用途，以及IP6在牙科中的应用。
