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一名从登革热中康复的免疫功能正常患者发生的毛霉病。

Mucormycosis in an Immunocompetent Patient Recovering From Dengue Fever.

作者信息

D J Sushmitha, Annapureddy Kalyan Kumar Reddy, Poojary Nishan, Balapanga Santhosh, Kumari Bindu

机构信息

Otolaryngology, ClearMedi Radiant Hospital, Mysuru, IND.

Internal Medicine, Sri Venkateswara Medical College, Tirupati, IND.

出版信息

Cureus. 2024 Jul 23;16(7):e65212. doi: 10.7759/cureus.65212. eCollection 2024 Jul.

DOI:10.7759/cureus.65212
PMID:39176311
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11340907/
Abstract

Mucormycosis is a rare yet aggressive fungal infection. Despite its rarity, India has experienced a surge in cases during the post-COVID-19 era. The high mortality rate associated with this infection necessitates early diagnosis, intervention, and aggressive treatment. Typically, it is observed in immunocompromised patients, where the disease progresses rapidly and leads to unfavorable outcomes. However, occurrences in previously healthy individuals are not uncommon. Dengue has been occasionally associated with mucormycosis in the post-recovery phase. This case report highlights the importance of heightened clinical suspicion and early intervention in patients with recent dengue infections and chronic sinus conditions. It explores potential risk factors, such as dengue-related immune alterations, environmental exposures, and anatomical alterations that may contribute to the development of mucormycosis in otherwise healthy individuals.

摘要

毛霉菌病是一种罕见但具有侵袭性的真菌感染。尽管其罕见，但在新冠疫情后时代，印度的病例数激增。这种感染相关的高死亡率需要早期诊断、干预和积极治疗。通常，它在免疫功能低下的患者中出现，疾病进展迅速并导致不良后果。然而，在先前健康的个体中发生也并不罕见。登革热在康复后期偶尔与毛霉菌病相关。本病例报告强调了对近期感染登革热和患有慢性鼻窦疾病的患者提高临床怀疑度和早期干预的重要性。它探讨了潜在的风险因素，如登革热相关的免疫改变、环境暴露以及可能导致原本健康的个体发生毛霉菌病的解剖学改变。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/d8259c4286f9/cureus-0016-00000065212-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/ff851f5ec778/cureus-0016-00000065212-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/90ee287b9b38/cureus-0016-00000065212-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/e04e8b723743/cureus-0016-00000065212-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/24702b88b22c/cureus-0016-00000065212-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/d8259c4286f9/cureus-0016-00000065212-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/ff851f5ec778/cureus-0016-00000065212-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/90ee287b9b38/cureus-0016-00000065212-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/e04e8b723743/cureus-0016-00000065212-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/24702b88b22c/cureus-0016-00000065212-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/624e/11340907/d8259c4286f9/cureus-0016-00000065212-i05.jpg

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