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减少恶臭的造口袋添加剂的有效性:气味强度、享乐色调和气味特征的评估

Effectiveness of Malodor-Reducing Ostomy Pouch Additives: An Assessment of Odor Intensity, Hedonic Tone, and Odor Character.

作者信息

Meacham Andrew, Gowans Philip, Bradley-Clarke Jack, Swearingen Anne, Lord Suzanne

机构信息

Sensory Testing, Olfasense UK Ltd., Bristol, GBR.

Ostomy Care, Convatec Ltd., Deeside, GBR.

出版信息

Cureus. 2024 Jul 23;16(7):e65172. doi: 10.7759/cureus.65172. eCollection 2024 Jul.

Abstract

Background Ostomy pouch odor can have a negative impact on the quality of life of people living with a stoma. This study assessed the effectiveness of malodor-reducing ostomy pouch additives under simulated conditions. Methodology The following six commercially available products with different odor control technologies plus a control were assessed: soyethyl morpholinium ethosulphate, zinc ricinoleate (ZnR), ZnR with orange terpenes (ZnR-Orange), a proprietary copper-based deodorant, a proprietary ion mix deodorant, and a terpene blend (TB). Each was added to an ostomy pouch with skatole (a substitute for human fecal odor). Professional olfactometrists rated odors according to intensity, hedonic tone (pleasantness), and character. Results The TB and ZnR-Orange had very weak (<1.0) malodor intensity, with mean (standard deviation [SD]) ratings of 0.6 (1.1) and 0.9 (0.9), respectively. All other products (2.7-3.0) and control (3.7) were statistically higher (stronger intensity) compared with the TB(p < 0.001). The mean (SD) hedonic tone for the TB was 0.8 (1.7) (considered slightly pleasant); all other products (-0.8 to 0.1) and control (-0.9) were statistically lower (p < 0.001). Odor character profiles were broadly comparable, but products with scent additives (TB and ZnR-Orange) were predominantly associated with fragrances. Conclusions This information may help nurses and other healthcare providers when educating ostomates about their options. Other factors such as application mode and recommended dosage may also influence the choice of product. Future research on real-world populations (i.e., ostomates), as well as assessment of lubrication properties, is warranted.

摘要

背景 造口袋异味会对造口患者的生活质量产生负面影响。本研究在模拟条件下评估了减少恶臭的造口袋添加剂的有效性。

方法 评估了以下六种具有不同气味控制技术的市售产品以及一个对照产品:乙基硫酸大豆乙吗啉、蓖麻醇酸锌(ZnR)、含橙萜烯的ZnR(ZnR-橙)、一种专利铜基除臭剂、一种专利离子混合除臭剂和一种萜烯混合物(TB)。将每种产品添加到含有粪臭素(一种替代人类粪便气味的物质)的造口袋中。专业嗅觉测定师根据强度、快感基调(愉悦度)和特征对气味进行评分。

结果 TB和ZnR-橙的恶臭强度非常弱(<1.0),平均(标准差[SD])评分分别为0.6(1.1)和0.9(0.9)。与TB相比,所有其他产品(2.7 - 3.0)和对照(3.7)在统计学上更高(强度更强)(p < 0.001)。TB的平均(SD)快感基调为0.8(1.7)(被认为略带愉悦);所有其他产品(-0.8至0.1)和对照(-0.9)在统计学上更低(p < 0.001)。气味特征大致可比,但含有香味添加剂的产品(TB和ZnR-橙)主要与香料有关。

结论 这些信息可能有助于护士和其他医疗保健提供者向造口患者介绍他们的选择。其他因素,如应用方式和推荐剂量,也可能影响产品的选择。有必要对实际人群(即造口患者)进行进一步研究,并评估润滑性能。

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