Ohonba Nosagie, Thorpe Devon, Gopal Yashini, Bhola Kiana, Jordanovski David
Department of Internal Medicine, Overlook Medical Center, Summit, USA.
Department of Internal Medicine, Overlook Medical Center, New Jersey, USA.
Cureus. 2024 Jul 23;16(7):e65183. doi: 10.7759/cureus.65183. eCollection 2024 Jul.
Congenital pulmonary airway malformations (CPAMs) are predominantly identified prenatally or during infancy, with adult-onset cases being considered extremely rare. This case report describes a 22-year-old male who presented with hemoptysis and exertional dyspnea, leading to the diagnosis of CPAM. The patient had experienced small-volume hemoptysis for four years, which escalated to larger volumes and progressive dyspnea one week before hospital admission. A chest CT scan revealed a large 13.2 cm thin-walled cavitary lesion with an air-fluid level in the left lower lobe. The patient underwent left video-assisted thoracoscopic surgery (VATS) resection, which confirmed a CPAM originating from the left lower lobe. The postoperative recovery was uneventful, and the patient was symptom-free at follow-up. This case highlights the need to consider CPAM in the differential diagnosis of respiratory symptoms in young adults, even without congenital anomalies or predisposing factors. Early recognition and surgical intervention can lead to favorable outcomes.
先天性肺气道畸形（CPAMs）主要在产前或婴儿期被发现，成人发病的病例极为罕见。本病例报告描述了一名22岁男性，他因咯血和劳力性呼吸困难就诊，最终被诊断为CPAM。该患者有少量咯血四年，入院前一周咯血增多且出现进行性呼吸困难。胸部CT扫描显示左肺下叶有一个13.2 cm的大型薄壁空洞性病变，内有气液平面。患者接受了左电视辅助胸腔镜手术（VATS）切除，证实为起源于左肺下叶的CPAM。术后恢复顺利，随访时患者无症状。该病例强调，即使没有先天性异常或易感因素，在年轻成人呼吸症状的鉴别诊断中也需要考虑CPAM。早期识别和手术干预可带来良好预后。
