阿尔茨海默病患者胼胝体的形态计量分析：磁共振成像（MRI）研究
Morphometric Analysis of Corpus Callosum in Individuals with Alzheimer's Disease: Magnetic Resonance Imaging (MRI) Study.
作者信息
Acar Musa, Uğur Sultan
机构信息
Department of Physiotherapy and Rehabilitation, Faculty of Nezahat Keleşoğlu Health Sciences, Necmettin Erbakan University, Konya, Turkey.
Department of Radiology, Pursaklar State Hospital, Ankara, Turkey.
出版信息
Curr Alzheimer Res. 2024;21(4):289-294. doi: 10.2174/0115672050335744240820065952.
INTRODUCTION
The Corpus Callosum (CC) is the largest commissural tract in the nervous system. Few studies have examined the extent of CC in Alzheimer's disease (AD) patients, and these studies have reported conflicting findings.
MATERIALS AND METHODS
The study was performed using 176 brain MRI images of 88 Alzheimer's patients (55 women-32 men) and 88 healthy individuals (44 women-44 men).
RESULTS
In our study, 7 different parameters of the CC were measured, and their average values were determined. We measured each parameter separately in AD patients and healthy individuals and compared them with each other.
CONCLUSION
CC has an important place not only in Patients with AD but also in other neurodegenerative diseases. We consider that our study will be useful in the evaluation of Patients with AD.
引言
胼胝体（CC）是神经系统中最大的连合纤维束。很少有研究考察过阿尔茨海默病（AD）患者的胼胝体范围，且这些研究报告的结果相互矛盾。
材料与方法
本研究使用了88名阿尔茨海默病患者（55名女性 - 32名男性）和88名健康个体（44名女性 - 44名男性）的176张脑部MRI图像。
结果
在我们的研究中，测量了胼胝体的7个不同参数，并确定了它们的平均值。我们分别在AD患者和健康个体中测量了每个参数，并相互进行比较。
结论
胼胝体不仅在AD患者中，而且在其他神经退行性疾病中都具有重要地位。我们认为我们的研究将有助于AD患者的评估。
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