Human Cardiovascular Physiology Laboratory, Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Human Performance and Health Research Laboratory, Department of Human Health and Nutritional Sciences, University of Guelph, Guelph, Ontario, Canada.
Am J Physiol Heart Circ Physiol. 2024 Oct 1;327(4):H947-H955. doi: 10.1152/ajpheart.00453.2024. Epub 2024 Aug 23.
Exaggerated blood pressure (BP) responses during exercise are independently associated with future development of hypertension. Partial sleep deprivation (PSD) can increase 24-h ambulatory BP, but the effects on exercise BP are unclear. We hypothesized that acute PSD would augment the BP response to constant load cycling exercise and a 20-min time trial. Twenty-two healthy adults (22 ± 3 yr old; 13 males; V̇o, 43.6 ± 8.2 mL·kg·min) completed a randomized crossover trial in which they either slept normally (normal sleep-wake schedule for each participant) or sleep was partially deprived (early awakening, 40% of normal sleep duration). Each participant completed a 12-min warm-up consisting of two 6-min steps (, 62 ± 25 W; , 137 ± 60 W) followed by a 20-min time trial on a cycle ergometer. PSD did not alter power output during the 20-min time trial [(control vs. PSD) 170 ± 68 vs. 168 ± 68 W, = 0.65]. Systolic BP did not differ during of the warm-up (141 ± 15 vs. 137 ± 12 mmHg, = 0.39) but was lower following PSD during (165 ± 21 vs. 159 ± 22 mmHg, = 0.004) and the 20-min time trial (171 ± 20 vs. 164 ± 23 mmHg, < 0.001). These results were maintained when peak oxygen uptake (V̇o) was included as a covariate. Systolic BP responses were modulated by sex (time × visit × sex interaction = 0.03), with attenuated systolic BP during the warm-up and the 20-min time trial in males but not in females. In contrast to our hypothesis, acute PSD attenuates systolic BP responses during constant load and 20-min time trial cycling exercise; however, these observations appear to be primarily driven by changes in males. A single night of partial sleep deprivation (PSD) can increase ambulatory blood pressure (BP) the following day. Despite this phenomenon, the present study found that acute PSD attenuates systolic BP responses to both constant load cycling and a 20-min cycling time trial in young healthy adults. Interestingly, the attenuated systolic BP responses following PSD appeared to be modulated by sex such that attenuations were observed in males but not in females.
过度的血压（BP）反应与未来高血压的发展独立相关。部分睡眠剥夺（PSD）可增加 24 小时动态血压，但对运动血压的影响尚不清楚。我们假设急性 PSD 会增强恒负荷循环运动和 20 分钟计时赛的 BP 反应。22 名健康成年人（22±3 岁；13 名男性；V̇o，43.6±8.2 mL·kg·min）完成了一项随机交叉试验，他们要么正常睡眠（每个参与者的正常睡眠-觉醒时间表），要么部分睡眠剥夺（提前醒来，正常睡眠时间的 40%）。每位参与者完成了 12 分钟的热身，包括两个 6 分钟的步骤（，62±25 W；，137±60 W），然后在自行车测功计上进行 20 分钟的计时赛。PSD 并没有改变 20 分钟计时赛期间的功率输出[（对照 vs. PSD）170±68 与 168±68 W，=0.65]。热身的前 （141±15 与 137±12 mmHg，=0.39）和最后 （165±21 与 159±22 mmHg，=0.004）时，收缩压没有差异，但 PSD 后收缩压较低，在 20 分钟计时赛中收缩压也较低（171±20 与 164±23 mmHg，<0.001）。当将峰值摄氧量（V̇o）作为协变量时，这些结果仍然保持不变。收缩压反应受性别调节（时间×访视×性别交互作用=0.03），男性在热身和 20 分钟计时赛期间收缩压降低，但女性没有。与我们的假设相反，急性 PSD 会减弱恒负荷和 20 分钟计时赛自行车运动时的收缩压反应；然而，这些观察结果似乎主要是由男性的变化引起的。一晚上的部分睡眠剥夺（PSD）会增加第二天的动态血压（BP）。尽管存在这种现象，但本研究发现，急性 PSD 会减弱年轻健康成年人对恒负荷循环运动和 20 分钟循环计时赛的收缩压反应。有趣的是，PSD 后收缩压的减弱似乎受到性别调节，在男性中观察到减弱，但在女性中没有。
