Mougin F, Bourdin H, Simon-Rigaud M L, Nguyen N U, Kantelip J P, Davenne D
UFR STAPS, Laboratoire des Sciences du Sport, Besançon, France.
J Sports Sci. 2001 Feb;19(2):89-97. doi: 10.1080/026404101300036253.
The aim of this study was to determine the hormonal responses, which are dependent on the sleep wake cycle, to strenuous physical exercise. Exercise was performed after different nocturnal regimens: (i) a baseline night preceded by a habituation night; (ii) two nights of partial sleep deprivation caused by a delayed bedtime or by an early awakening; and (iii) two nights of sleep after administration of either a hypnotic compound (10 mg zolpidem) or a placebo. Eight well-trained male endurance athletes with a maximal oxygen uptake of 63.5 +/- 3.8 ml x kg(-1) x min(-1) (mean value +/- s(x)) were selected on the basis of their sleeping habits and their physical training. Polygraphic recordings of EEG showed that both nights with partial sleep loss led to a decrease (P< 0.01) in stage 2 and rapid eye movement sleep. A delayed bedtime also led to a decrease (P < 0.05) in stage 1 sleep. Zolpidem had no effect on the different stages of sleep. During the afternoon after an experimental night, exercise was performed on a cycle ergometer. After a 10-min warm-up, the participants performed 30 min steady-state cycling at 75% VO(2-max) followed by a progressively increased workload until exhaustion. The recovery period lasted 30 min. Plasma growth hormone, prolactin, cortisol, catecholamine and lactate concentrations were measured at rest, during exercise and after recovery. The concentration of plasma growth hormone and catecholamine were not affected by partial sleep deprivation, whereas that of plasma prolactin was higher (P < 0.05) during the trial after an early awakening. Plasma cortisol was lower (P < 0.05) during recovery after both sleep deprivation conditions. Blood lactate was higher (P < 0.05) during submaximal exercise performed after both a delayed bedtime and an early awakening. Zolpidem-induced sleep did not affect the hormonal and metabolic responses to subsequent exercise. Our results demonstrate only minor alterations in the hormonal responses to exercise after partial sleep deprivation.
本研究的目的是确定依赖于睡眠-清醒周期的激素对剧烈体育锻炼的反应。在不同的夜间作息方案后进行锻炼：(i) 在适应夜之后的基线夜；(ii) 因就寝时间延迟或早起导致的两晚部分睡眠剥夺；(iii) 服用催眠化合物（10毫克唑吡坦）或安慰剂后两晚的睡眠。根据他们的睡眠习惯和体育训练情况，选择了8名训练有素的男性耐力运动员，其最大摄氧量为63.5±3.8毫升×千克(-1)×分钟(-1)（平均值±标准误）。脑电图的多导记录显示，两晚部分睡眠缺失均导致第2阶段和快速眼动睡眠减少（P<0.01）。就寝时间延迟也导致第1阶段睡眠减少（P<0.05）。唑吡坦对睡眠的不同阶段没有影响。在实验夜后的下午，在自行车测力计上进行锻炼。经过10分钟的热身，参与者以75%的最大摄氧量进行30分钟的稳态骑行，随后工作量逐渐增加直至疲劳。恢复期持续30分钟。在休息、运动期间和恢复后测量血浆生长激素、催乳素、皮质醇、儿茶酚胺和乳酸浓度。血浆生长激素和儿茶酚胺的浓度不受部分睡眠剥夺的影响，而在早起后的试验期间，血浆催乳素的浓度较高（P<0.05）。在两种睡眠剥夺条件后的恢复期间，血浆皮质醇较低（P<0.05）。在就寝时间延迟和早起后进行的次最大运动期间，血乳酸较高（P<0.05）。唑吡坦诱导的睡眠不影响对随后运动的激素和代谢反应。我们的结果表明，部分睡眠剥夺后激素对运动的反应仅有轻微改变。
