snoRNAs 在制造“snoman”核糖体中发挥作用。
snoRNAs in making "snoman" ribosomes.
机构信息
Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA.
Department of Urology, University of California, San Francisco, San Francisco, CA 94158, USA; Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94158, USA; Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA.
出版信息
Mol Cell. 2024 Aug 22;84(16):3008-3010. doi: 10.1016/j.molcel.2024.07.029.
In a recent study in Cell, Cheng and Wang et al. show that the small nucleolar RNA (snoRNA) SNORA13 has a non-canonical role in ribosome biogenesis and senescence by acting directly on RPL23 and regulating its assembly into the 60S ribosomal subunit.
在最近发表在《Cell》杂志上的一项研究中，程和平和王宏伟等研究人员发现，核仁小 RNA（snoRNA） SNORA13 通过直接作用于 RPL23 并调节其组装到 60S 核糖体亚基中，在核糖体生物发生和衰老中发挥非典型作用。
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