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技术现状综述:婴幼儿主动脉瓣修复术

State of the Art Review: Aortic Valve Repair in Infants and Children.

作者信息

Chiu Peter, Higgins Harrison A, Baird Christopher W

机构信息

Department of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts.

Department of Cardiac Surgery, Boston Children's Hospital, Boston, Massachusetts.

出版信息

Ann Thorac Surg. 2025 Mar;119(3):697-707. doi: 10.1016/j.athoracsur.2024.07.043. Epub 2024 Aug 22.

Abstract

BACKGROUND

Congenital aortic and truncal valve disease is challenging in infants and children given the lack of available prostheses in very small sizes and the limited durability of homograft aortic valve replacement.

METHODS

A comprehensive literature search was performed using the PubMed database. Studies were included either if the report included patients less than 1 year of age or if the technique was tailored to accommodate for somatic growth.

RESULTS

Techniques for aortic and truncal valve repair addressing each aspect of the aortic valve complex-the aorta, aortic annulus, commissures, and cusps-were reviewed. The incidence of reoperation after aortic or truncal valve repair is significant at 10 years and ranges from 30% to 70% depending on the underlying diagnosis and the repair technique used. A significant challenge in interpreting the published literature relates to the lack of anatomic data available in the publications, thus limiting both the ability to make direct comparisons among operative techniques and the ability to draw conclusions regarding these techniques as applied to varied causes.

CONCLUSIONS

A comprehensive understanding of the aortic valve complex is necessary to achieve adequate results in pediatric aortic valve repair given the high variability in these valves.

摘要

背景

由于缺乏非常小尺寸的可用假体以及同种异体主动脉瓣置换术的耐久性有限,先天性主动脉瓣和动脉干瓣膜疾病在婴幼儿中具有挑战性。

方法

使用PubMed数据库进行了全面的文献检索。如果报告包括1岁以下的患者,或者该技术是为适应身体生长而量身定制的,则纳入研究。

结果

回顾了针对主动脉瓣复合体各个方面(主动脉、主动脉瓣环、瓣叶交界和瓣叶)的主动脉瓣和动脉干瓣膜修复技术。主动脉瓣或动脉干瓣膜修复术后10年再次手术的发生率很高,根据潜在诊断和所使用的修复技术,发生率在30%至70%之间。解读已发表文献的一个重大挑战在于文献中缺乏可用的解剖学数据,这既限制了对手术技术进行直接比较的能力,也限制了就这些技术应用于不同病因得出结论的能力。

结论

鉴于这些瓣膜的高度变异性,要在小儿主动脉瓣修复中取得满意的结果,对主动脉瓣复合体有全面的了解是必要的。

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