Department of Lymphatic Oncology, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, China.
Department of Nursing, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Third Hospital of Shanxi Medical University, Tongji Shanxi Hospital, Taiyuan, China
BMJ Open. 2024 Aug 22;14(8):e082822. doi: 10.1136/bmjopen-2023-082822.
Symptom networks offer a theoretical basis for developing personalised and precise symptom management strategies. However, symptom networks in lymphoma patients during chemotherapy have been rarely reported. This study intends to establish contemporaneous symptom networks in lymphoma patients during chemotherapy and explore the centrality indices and density in these symptom networks.
This is a single-centre prospective cross-sectional study. A total of 315 lymphoma patients admitted to the Lymphoma Department of Shanxi Bethune Hospital since 1 June 2024 will be selected as the study subjects. The patient-reported outcome measures of General Data Questionnaire and Lymphoma Symptom Assessment Scale will be assessed. R package will be used to construct a contemporaneous symptom network, explore the relationship between core and analysed symptoms and analyse the predictive role of network density on patient prognosis.
This study adheres to the principles of the Declaration of Helsinki and relevant ethical guidelines. Ethical approval has been obtained from Shanxi Bethune Hospital Ethics Committee (approval number: YXLL-2023-186). The final outcomes will be published in a peer-reviewed journal and disseminated through a conference.
症状网络为制定个性化和精准的症状管理策略提供了理论基础。然而，化疗期间淋巴瘤患者的症状网络却鲜有报道。本研究旨在建立化疗期间淋巴瘤患者的同期症状网络，并探讨这些症状网络中的中心性指数和密度。
这是一项单中心前瞻性横断面研究。将于 2024 年 6 月 1 日起，选取山西白求恩医院淋巴瘤科收治的 315 例淋巴瘤患者作为研究对象。将评估患者报告的一般数据问卷和淋巴瘤症状评估量表的结果。使用 R 包构建同期症状网络，探讨核心症状与分析症状之间的关系，并分析网络密度对患者预后的预测作用。
本研究遵循《赫尔辛基宣言》和相关伦理准则。山西白求恩医院伦理委员会已批准本研究（批准号：YXLL-2023-186）。最终结果将发表在同行评议的期刊上，并通过会议进行传播。
