Xiangya School of Nursing, Central South University, Changsha, China.
The Third Xiangya Hospital, Central South University, Changsha, China.
Support Care Cancer. 2023 Apr 25;31(5):297. doi: 10.1007/s00520-023-07759-7.
During chemotherapy for multiple myeloma, symptoms include those related to the disease, as well as adverse effects of the treatment. Few studies have explored the relationships between these symptoms. Network analysis could identify the core symptom in the symptom network.
The aim of this study was to explore the core symptom in multiple myeloma patients undergoing chemotherapy.
This was a cross-sectional study in which sequential sampling was used to recruit 177 participants from Hunan, China. Demographic and clinical characteristics were surveyed using a self-developed instrument. The symptoms of chemotherapy-treated multiple myeloma, including pain, fatigue, worry, nausea, and vomiting, were measured using a questionnaire with good reliability and validity. The mean ± SD, frequency, and percentages were used as descriptive statistics. Network analysis was used to estimate the correlation between symptoms.
The results showed that 70% of multiple myeloma patients using chemotherapy exhibited pain. In the network analysis, worrying was the dominant symptom, and the strongest relationship was between nausea and vomiting in chemotherapy-treated multiple myeloma patients' symptoms.
Worrying is the core symptom of multiple myeloma patients. Interventions could be most effective if there is a symptom management focus on worrying when providing care to chemotherapy-treated multiple myeloma patients. Nausea combined with vomiting could be better managed, which would decrease the cost of health care. Understanding the relationship between the symptoms of multiple myeloma patients undergoing chemotherapy is beneficial for precise symptom management.
Nurses and health care teams should be a priority to intervene in the worrying for chemotherapy-treated multiple myeloma patients to maximize the effectiveness of an intervention. Except, nausea and vomiting should be managed together in a clinical setting.
在多发性骨髓瘤的化疗过程中，症状既包括与疾病相关的症状，也包括治疗的不良反应。很少有研究探讨这些症状之间的关系。网络分析可以确定症状网络中的核心症状。
本研究旨在探讨正在接受化疗的多发性骨髓瘤患者的核心症状。
这是一项横断面研究，采用连续抽样法从中国湖南招募了 177 名参与者。使用自行设计的仪器调查人口统计学和临床特征。使用具有良好信度和效度的问卷测量化疗治疗多发性骨髓瘤的症状，包括疼痛、疲劳、担忧、恶心和呕吐。采用均数±标准差、频率和百分比进行描述性统计。网络分析用于估计症状之间的相关性。
结果表明，70%的化疗多发性骨髓瘤患者存在疼痛。在网络分析中，担忧是主要症状，恶心和呕吐在化疗治疗多发性骨髓瘤患者的症状之间存在最强的关系。
担忧是多发性骨髓瘤患者的核心症状。如果在为化疗治疗多发性骨髓瘤患者提供护理时，将关注重点放在担忧症状上，那么干预措施可能最有效。恶心合并呕吐可能更容易管理，这将降低医疗保健成本。了解化疗治疗多发性骨髓瘤患者的症状之间的关系有助于进行精确的症状管理。
护士和医疗保健团队应优先干预化疗治疗多发性骨髓瘤患者的担忧，以最大限度地提高干预措施的效果。此外，在临床环境中应同时管理恶心和呕吐。
