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女性中伪装成青少年血管纤维瘤的肿瘤;揭示了一种罕见的鼻窦组织病理学——血管外皮细胞瘤。

Tumour masquerading juvenile angiofibroma in a female; unveiling glomangiopericytoma-a rare sinonasal histopathology.

机构信息

ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India

ENT, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India.

出版信息

BMJ Case Rep. 2024 Aug 24;17(8):e256667. doi: 10.1136/bcr-2023-256667.

Abstract

Sinonasal tumours of varying histology are not unusual in otolaryngology surgical practice. Juvenile angiofibroma (JAs) are vascular tumours usually occurring in adolescent male population; but rare in females. But similar clinical and radiological presentations are possible in females inducing strong suspicion of JA which needs to be ruled out by detailed evaluation. Here we present a case of a young female in her 20s who presented with a bleeding nasal mass which was finally diagnosed as sinonasal glomangiopericytoma which is a very rare sinonasal tumour. Tumours resembling JA do present in the female population but rarely turn out to be JA. A strong index of suspicion along with a handful of special blood investigations to rule out androgen insensitivity syndrome is mandatory.

摘要

在耳鼻喉科手术实践中,各种组织学的鼻腔鼻窦肿瘤并不罕见。青少年血管纤维瘤(JAs)是一种血管肿瘤,通常发生在青少年男性中;但在女性中很少见。但女性可能会出现类似的临床和影像学表现,强烈怀疑 JA,需要通过详细评估排除。在这里,我们介绍了一位 20 多岁的年轻女性,她因鼻腔出血性肿块就诊,最终被诊断为鼻腔鼻窦血管外皮细胞瘤,这是一种非常罕见的鼻腔鼻窦肿瘤。类似于 JA 的肿瘤确实也会出现在女性人群中,但很少是 JA。强烈的怀疑指数,以及少数特殊的血液检查以排除雄激素不敏感综合征是必需的。

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