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二维胎儿脑超声分析基准

A benchmark for 2D foetal brain ultrasound analysis.

机构信息

Brain and Mind Centre, University of Sydney, Sydney, Australia.

Faculty Of Science, Yamagata University, Yamagata, Japan.

出版信息

Sci Data. 2024 Aug 24;11(1):923. doi: 10.1038/s41597-024-03774-3.

Abstract

Brain development involves a sequence of structural changes from early stages of the embryo until several months after birth. Currently, ultrasound is the established technique for screening due to its ability to acquire dynamic images in real-time without radiation and to its cost-efficiency. However, identifying abnormalities remains challenging due to the difficulty in interpreting foetal brain images. In this work we present a set of 104 2D foetal brain ultrasound images acquired during the 20th week of gestation that have been co-registered to a common space from a rough skull segmentation. The images are provided both on the original space and template space centred on the ellipses of all the subjects. Furthermore, the images have been annotated to highlight landmark points from structures of interest to analyse brain development. Both the final atlas template with probabilistic maps and the original images can be used to develop new segmentation techniques, test registration approaches for foetal brain ultrasound, extend our work to longitudinal datasets and to detect anomalies in new images.

摘要

脑发育涉及胚胎早期到出生后几个月的一系列结构变化。目前,由于超声能够实时获取动态图像、无辐射且具有成本效益,因此是筛查的既定技术。然而,由于难以解释胎儿脑图像,因此识别异常仍然具有挑战性。在这项工作中,我们展示了一组在妊娠第 20 周采集的 104 张 2D 胎儿脑超声图像,这些图像已经从粗略的颅骨分割中配准到共同空间。这些图像以原始空间和以所有受试者椭圆为中心的模板空间提供。此外,这些图像已经进行了注释,突出了感兴趣结构的地标点,以分析大脑发育。最终的图谱模板和概率图以及原始图像都可以用于开发新的分割技术、测试胎儿脑超声的配准方法、将我们的工作扩展到纵向数据集以及检测新图像中的异常。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b56/11344807/8cc9051400b0/41597_2024_3774_Fig1_HTML.jpg

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