社会决定因素与慢性肾脏病儿童的生活质量：来自沙特阿拉伯的见解。

Social determinants of health and quality of life in children with chronic kidney disease: insights from Saudi Arabia.

机构信息

Section of Nephrology, Department of Pediatrics, Children's Specialized Hospital, King Fahad Medical City, Riyadh, Kingdom of Saudi Arabia.

College of Medicine, King Saud University, Riyadh, Saudi Arabia.

出版信息

BMC Nephrol. 2024 Aug 24;25(1):272. doi: 10.1186/s12882-024-03710-y.

DOI:10.1186/s12882-024-03710-y

PMID:39182016

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11344921/

Abstract

BACKGROUND

Social determinants of health (SDoH) are increasingly recognized as crucial factors affecting the well-being of pediatric chronic kidney disease (CKD) patients. This study explores the impact of SDoH on the quality of life (QoL) of children with CKD in Saudi Arabia.

METHODS

This observational, descriptive, cross-sectional study included 50 participants with CKD stages three to five, as well as children with end-stage renal disease (ESRD) undergoing peritoneal dialysis (PD) or hemodialysis (HD) in Riyadh, Saudi Arabia. Data were collected from children and their caregivers using a validated Arabic-adapted version of the Pediatric Quality of Life Inventory (PedsQL) 3.0 and an SDoH survey.

RESULTS

The study revealed that access to education significantly affects pediatric QoL (H/Z score 2.825; P-value 0.005), and the lack of dietary recommendations was identified as a critical factor (H/Z score 1.441; P-value 0.029). ESRD patients on PD from larger families reported better QoL, whereas lower family income was associated with reduced QoL in PD patients (P-value 0.048). Compared to those in earlier stages of CKD, ESRD patients showed lower QoL (H/Z score 2.154; P-value 0.031).

CONCLUSION

Our study provides initial insights into the relationship between SDoH and the QoL of children with CKD in Saudi Arabia. It calls for a comprehensive approach that includes these determinants in care strategies to improve patient outcomes and QoL.

摘要

背景

健康的社会决定因素（SDoH）日益被认为是影响儿科慢性肾脏病（CKD）患者健康的关键因素。本研究旨在探讨 SDoH 对沙特阿拉伯儿童 CKD 患者生活质量（QoL）的影响。

方法

本观察性、描述性、横断面研究纳入了沙特阿拉伯利雅得的 50 名 CKD 三至五期患儿以及接受腹膜透析（PD）或血液透析（HD）治疗的终末期肾病（ESRD）患儿。使用经阿拉伯语改编的儿童生活质量量表（PedsQL）3.0 及 SDoH 调查评估工具收集了患儿及其照护者的数据。

结果

研究表明，获得教育的机会显著影响儿科 QoL（H/Z 评分 2.825；P 值 0.005），缺乏饮食建议被认为是一个关键因素（H/Z 评分 1.441；P 值 0.029）。来自大家庭的 PD 治疗 ESRD 患儿报告 QoL 更好，而 PD 患儿的家庭收入较低则与 QoL 降低相关（P 值 0.048）。与 CKD 早期阶段的患儿相比，ESRD 患儿的 QoL 较低（H/Z 评分 2.154；P 值 0.031）。