Al Wakeel Jamal, Al Harbi Ali, Bayoumi Magda, Al-Suwaida Karaem, Al Ghonaim Mohammed, Mishkiry Adel
Department of Medicine, Nephrology Unit, King Saud University, Department of Medicine (38) P.O. Box 2925 Riyadh 11461, Saudi Arabia.
Ann Saudi Med. 2012 Nov-Dec;32(6):570-4. doi: 10.5144/0256-4947.2012.570.
Quality of life (QoL) in end-stage renal disease (ESRD) patients is an important outcome for both physicians and patients in selecting dialysis modality. We conducted a comparison between regular maintenance hemodiaylsis and regular peritoneal dialysis patients in two tertiary referral hospitals in King Saud University in Saudi Arabia. We hypothesize that there might be cultural and socioeconomic factors modifying QoL in dialysis patients.
Cross-sectional study on hemodialysis and peritoneal dialysis patients.
Two hundred dialysis patients participated in the study, one hundred in each group of dialysis modality, from July 2007 to July 2008. We used a cross-sectional design and collected the date using the Kidney Disease Quality of Life (KDQoL SF) questionnaire.
Patients in both groups had similar sociodemographic characteristics (age, marital status, and education). Mean age (SD) in the hemodialysis group was 47.5 (13.8) years and 51.0 (13.5) years in the peritoneal dialysis group. Males represented 53% and 43%, respectively. Mean duration of dialysis was 77.2 (75.5) months in the hemodialysis group and 34.1 (26.9) months in the peritoneal dialysis group. The mean (SD) score was 49.5 (13.7) in the hemodialysis group and 61.3 (12.4) in the peritoneal dialysis group. QoL mean scores were significantly higher among peritoneal dialysis in all domains and in the total QoL, with the exception of the score of physical QoL, which was higher in the hemodialysis patients, compared to peritoneal dialysis patients, although the difference was not statistically significant. Multiple regression analysis indicated that hemodialysis was a negative predictor of QoL score, compared to peritoneal dialysis. Also, age, male gender, and dialysis duration were negative predictors of QoL score.
In the unique culture of Saudi Arabia, peritoneal dialysis patients have better QoL, compared to hemodialysis patients, validating the findings of research reports from other countries.
终末期肾病(ESRD)患者的生活质量(QoL)是医生和患者选择透析方式时的一项重要结果。我们在沙特阿拉伯国王沙特大学的两家三级转诊医院对常规维持性血液透析患者和常规腹膜透析患者进行了比较。我们假设可能存在文化和社会经济因素影响透析患者的生活质量。
对血液透析和腹膜透析患者的横断面研究。
2007年7月至2008年7月,200名透析患者参与了该研究,每种透析方式各100名。我们采用横断面设计,并使用肾脏疾病生活质量(KDQoL SF)问卷收集数据。
两组患者在社会人口学特征(年龄、婚姻状况和教育程度)方面相似。血液透析组的平均年龄(标准差)为47.5(13.8)岁,腹膜透析组为51.0(13.5)岁。男性分别占53%和43%。血液透析组的平均透析时长为77.2(75.5)个月,腹膜透析组为34.1(26.9)个月。血液透析组的平均(标准差)得分为49.5(13.7),腹膜透析组为61.3(12.4)。除了身体生活质量得分外,腹膜透析患者在所有领域和总体生活质量方面的平均得分均显著高于血液透析患者,尽管差异无统计学意义,但血液透析患者的身体生活质量得分高于腹膜透析患者。多元回归分析表明,与腹膜透析相比,血液透析是生活质量得分的负预测因素。此外,年龄、男性性别和透析时长也是生活质量得分的负预测因素。
在沙特阿拉伯独特的文化背景下,与血液透析患者相比腹膜透析患者的生活质量更好,这证实了其他国家研究报告的结果。