The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), 54 Youdian Road, Hangzhou, Zhejiang Province, 310053, China.
BMC Musculoskelet Disord. 2024 Aug 24;25(1):666. doi: 10.1186/s12891-024-07776-5.
Xanthoma typically occurs in the subcutaneous tissues, with rare cases of xanthoma in the joints. However, the case of knee joint osteonecrosis combined with xanthoma is even more uncommon. In this article, we described a 50-year-old female patient who suffered xanthoma in the knee joint on the basis of osteonecrosis of the knee joint. The primary clinical symptoms were knee joint pain and limited mobility. The patient initially received conventional treatment for osteonecrosis. However, there was no significant improvement. Later, we found a synovial xanthoma in the patient's knee. Finally, she underwent arthroscopic excision of the knee joint synovial xanthoma. Following the procedure, her VAS score decreased from 7 to 2, and knee joint mobility increased from 10-103° to 10-140°. Through our follow-up, the patient did not exhibit symptom recurrence. This case is valuable as it provides a feasible therapeutic approach for future clinical applications.
黄色瘤通常发生于皮下组织，关节内黄色瘤少见。然而，膝关节骨坏死合并黄色瘤的病例更为罕见。本文报道了 1 例 50 岁女性患者，在膝关节骨坏死的基础上发生膝关节黄色瘤。主要临床症状为膝关节疼痛和活动受限。患者最初接受常规的骨坏死治疗，但无明显改善。后来，我们在患者的膝关节中发现滑膜黄色瘤。最终，行膝关节镜滑膜黄色瘤切除术。术后，患者的 VAS 评分从 7 分降至 2 分，膝关节活动度从 10°-103°增加至 10°-140°。通过随访，患者未出现症状复发。该病例为未来的临床应用提供了一种可行的治疗方法，具有重要价值。
