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两种狼疮抗凝物简易检测方法的比较

Comparison of two simple tests for the lupus anticoagulant.

作者信息

Exner T

出版信息

Am J Clin Pathol. 1985 Feb;83(2):215-8. doi: 10.1093/ajcp/83.2.215.

Abstract

Mixtures of various patient lupus inhibitor-containing plasmas and normal plasma were tested concurrently with the dilute tissue thromboplastin inhibition (DTTI) test and the kaolin clotting time (KCT). The KCT was found to be more sensitive to the presence of the lupus inhibitor than the DTTI. The principle of reducing the platelet phospholipid content in the KCT test plasma to enhance sensitivity for the lupus inhibitor was extended by using plasmas filtered through 0.22-micron cellulose acetate filters.

摘要

将各种含有患者狼疮抑制剂的血浆与正常血浆的混合物,同时用稀释组织凝血活酶抑制试验(DTTI)和白陶土凝血时间(KCT)进行检测。结果发现,KCT对狼疮抑制剂的存在比DTTI更敏感。通过使用经0.22微米醋酸纤维素滤器过滤的血浆,扩展了在KCT试验血浆中降低血小板磷脂含量以提高对狼疮抑制剂敏感性的原理。

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