RATIONALE

Ameloblastic fibro-odontoma (AFO) is a rare mixed odontogenic tumour with a preferential location in the posterior mandible and with a variety of radiological aspects. We report two clinical cases of AFO in two rare locations and with unusual radiological aspects.

PATIENT CONCERNS

The first patient is a 37-year-old female with an asymptomatic intraoral swelling located in the anterior mandibular. The second patient is a 16-year-old girl with a chief complaint of missing maxillary canine.

DIAGNOSIS

Both cases were diagnosed with AFO.

TREATMENT

For the first patient, a biopsy was performed, and for the second one, the lesion was surgically excised.

OUTCOMES

The first patient is under regular surveillance and the other was followed up for one year without any evidence of recurrences.

TAKE-AWAY LESSONS: Despite many efforts, the nature, histology and therapy of these lesions remain very confusing.