Mohamed Fatema, Vijayan Balasubramaniam, Saraswat Lokesh
Gastroenterology and Hepatology, Aberdeen Royal Infirmary Hospital, Aberdeen, GBR.
Radiology, Aberdeen Royal Infirmary Hospital, Aberdeen, GBR.
Cureus. 2024 Jul 24;16(7):e65289. doi: 10.7759/cureus.65289. eCollection 2024 Jul.
IgG4-related autoimmune pancreatitis (AIP) is a rare inflammatory condition characterized by elevated IgG4-positive plasma cells and lymphoplasmacytic infiltration in the pancreas. This disease responds to steroid therapy but can be challenging to differentiate from pancreatic cancer. In this paper, we present two cases of IgG4-related AIP presenting as pancreatic masses. Our aim is to highlight the diagnostic complexities of this condition and emphasize the need for a multidisciplinary approach to avoid unnecessary surgical interventions and ensure appropriate treatment.
IgG4 相关性自身免疫性胰腺炎(AIP)是一种罕见的炎症性疾病,其特征为胰腺中 IgG4 阳性浆细胞增多和淋巴浆细胞浸润。这种疾病对类固醇治疗有反应,但与胰腺癌进行鉴别可能具有挑战性。在本文中,我们介绍了两例表现为胰腺肿块的 IgG4 相关性 AIP 病例。我们的目的是强调这种疾病诊断的复杂性,并强调需要采用多学科方法以避免不必要的手术干预并确保进行适当的治疗。