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产褥期产妇感染病因:病例报告

Maternal puerperal infection caused by : a case report.

作者信息

Peng Liwei, Chen Xiaomin, Wang Zhenhui, Yi Lu, Jin Zhengjiang

机构信息

Department of Clinical Laboratory, Maternal and Child Health Hospital of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Department of Disinfection and Pest Control, Wuhan Center for Disease Control & Prevention, Wuhan, Hubei, China.

出版信息

Front Med (Lausanne). 2024 Aug 9;11:1450931. doi: 10.3389/fmed.2024.1450931. eCollection 2024.

Abstract

BACKGROUND

a member of the , was initially discovered in the feces and abdominal tissue of patients with appendicitis, peritonitis, and abdominal abscesses. In recent years, has been widely regarded as a gut probiotic, and human infections have been extremely rare. In 2010, was first isolated from the blood culture of a patient with abdominal infection, confirming its ability to cause bacteremia. In this study, we report a rare case of puerperal infection with septic shock caused by infection in a pregnant woman.

CASE PRESENTATION

A 31-year-old female experienced perineal lacerations, cervical lacerations, and postpartum hemorrhage during childbirth. Nine days postpartum, the patient developed septic shock, and infection was identified through blood culture and mass spectrometry. We administered broad-spectrum antibiotics, including meropenem/nalidixic acid and piperacillin tazobactam, intravenously, but the antimicrobial effect was not satisfactory. Upon ultrasound examination, we identified a focus of infection in the patient's uterus. Subsequently, uterine curettage was performed, followed by uterine cavity irrigation with metronidazole and intramuscular injection of gentamicin and dexamethasone. Following treatment, the patient's physiological parameters gradually returned to normal, and she was discharged 30 days after admission.

CONCLUSION

bacteraemia is extremely rare, and clinically, the postinfection toxicity of this bacterium appears to be significant. In this report, we review the research history of and relevant infection cases, aiming to enhance awareness among clinical practitioners, particularly obstetricians and gynecologists, regarding bloodstream infections, facilitating early diagnosis and timely treatment.

摘要

背景

[细菌名称]的一个成员最初是在阑尾炎、腹膜炎和腹部脓肿患者的粪便及腹部组织中发现的。近年来,[细菌名称]被广泛认为是一种肠道益生菌,人类感染极为罕见。2010年,首次从一名腹部感染患者的血培养物中分离出[细菌名称],证实了其引起菌血症的能力。在本研究中,我们报告了一例罕见的孕妇因[细菌名称]感染导致产褥感染并伴有感染性休克的病例。

病例介绍

一名31岁女性在分娩期间出现会阴裂伤、宫颈裂伤和产后出血。产后九天,患者发生感染性休克,通过血培养和质谱法鉴定为[细菌名称]感染。我们静脉注射了包括美罗培南/萘啶酸和哌拉西林他唑巴坦在内的广谱抗生素,但抗菌效果不理想。经超声检查,我们在患者子宫内发现了一个感染灶。随后进行了刮宫术,接着用甲硝唑进行宫腔冲洗,并肌肉注射庆大霉素和地塞米松。治疗后,患者的生理参数逐渐恢复正常,入院30天后出院。

结论

[细菌名称]菌血症极为罕见,临床上,这种细菌的感染后毒性似乎很大。在本报告中,我们回顾了[细菌名称]的研究历史及相关感染病例,旨在提高临床医生,特别是妇产科医生对[细菌名称]血流感染的认识,促进早期诊断和及时治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dca7/11341351/9e70745fe53e/fmed-11-1450931-g001.jpg

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