Lampe Elizabeth W, Muench Alexandria, Perlis Michael, Juarascio Adrienne S, Manasse Stephanie M
Center for Weight Eating & Lifestyle Science (WELL Center), Drexel University, Philadelphia, Pennsylvania, USA.
Department of Psychological and Brain Sciences, Drexel University, Philadelphia, USA.
Eat Disord. 2024 Aug 26:1-12. doi: 10.1080/10640266.2024.2394262.
Global sleep disturbance is robustly linked with a subjective sense of loss-of-control over eating (LOC). Depressed mood has been proposed as a mechanism to explain the bi-directional relationship between sleep disturbance and LOC eating. The current study evaluated whether sleep disturbance indirectly affects LOC eating via depressed mood. Adults seeking treatment for a DSM-5 binge-spectrum eating disorder (e.g. bulimia nervosa, binge-eating disorder) were recruited ( = 79) and asked to complete self-report questionnaires assessing sleep disturbance and depression, and a semi-structured interview assessing LOC eating. Tests of indirect effects evaluated the effect of depressed mood on the association between global sleep disturbance and LOC frequency covarying for BMI and parent study. A significant indirect effect of depressed mood on the association between global sleep disturbance and frequency of LOC eating was identified ( = 1.519, . = 0.859, = .033). The indirect effect of depressed mood on the association between sleep disturbance and LOC eating may indicate that depressed mood serves as a mechanistic link between sleep disturbance and LOC eating. The findings offer preliminary support for adjunctive treatments targeting both sleep disturbance and depressed mood for LOC eating. Future research should explore these pathways in a larger clinical sample.
全球睡眠障碍与进食失控的主观感受（LOC）密切相关。抑郁情绪被认为是解释睡眠障碍与LOC进食之间双向关系的一种机制。当前研究评估了睡眠障碍是否通过抑郁情绪间接影响LOC进食。招募了寻求治疗DSM-5暴食谱系进食障碍（如神经性贪食症、暴食障碍）的成年人（n = 79），并要求他们完成评估睡眠障碍和抑郁的自我报告问卷，以及评估LOC进食的半结构化访谈。间接效应测试评估了抑郁情绪对全球睡眠障碍与LOC频率之间关联的影响，同时考虑了BMI和母研究的协变量。确定了抑郁情绪对全球睡眠障碍与LOC进食频率之间关联的显著间接效应（β = 1.519，SE = 0.859，p = 0.033）。抑郁情绪对睡眠障碍与LOC进食之间关联的间接效应可能表明，抑郁情绪是睡眠障碍与LOC进食之间的一种机制联系。这些发现为针对睡眠障碍和抑郁情绪的LOC进食辅助治疗提供了初步支持。未来的研究应在更大的临床样本中探索这些途径。
