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暴饮暴食症患者的睡眠障碍、夜间进食与抑郁

Sleep disturbances, night eating, and depression in patients with binge-eating disorder.

作者信息

Velimirović Mina, Campione Marie, Manwaring Jamie, Rienecke Renee D, Riddle Megan, Duffy Alan, Mehler Philip S, Joiner Thomas E

机构信息

Department of Psychology, Faculty of Philosophy, University of Novi Sad, Serbia; Department of Psychology, Florida State University, Tallahassee, FL, USA.

Department of Psychology, Florida State University, Tallahassee, FL, USA.

出版信息

J Psychiatr Res. 2025 Sep;189:488-494. doi: 10.1016/j.jpsychires.2025.07.008. Epub 2025 Jul 30.

Abstract

Patients with binge-eating disorder (BED) frequently also meet the criteria for night-eating syndrome (NES). While both conditions are associated with elevated depression, it is less clear whether different features of night eating, including evening hyperphagia (EH) and nocturnal ingestions (NI), contribute to depression in individuals with a primary diagnosis of BED. Moreover, sleep disturbances, common in patients with BED, are also highly relevant for both NES and depression. Thus, using a sample of patients diagnosed with BED (N = 153), the present study examined the relationships between eating disturbances, including EH and NI, sleep disturbances, including initial insomnia (i.e., difficulty initiating sleep) and nocturnal awakenings, and depression. Initial insomnia, nocturnal awakenings, and EH were significantly associated with depression; NI was not. The results of a hierarchical linear regression showed that initial insomnia and nocturnal awakenings, but not EH, significantly contribute to depression, above and beyond global eating disorder pathology. Together, our results suggest that among patients with BED, in whom eating is already largely disrupted, EH and NI may not pose an additional risk for depression. In contrast, disrupted sleep does seem to confer a risk for depression, suggesting that a careful assessment of sleeping patterns in addition to eating patterns should be imperative in treatment-seeking patients with BED.

摘要

暴饮暴食症(BED)患者常常也符合夜间进食综合征(NES)的标准。虽然这两种病症都与抑郁情绪加剧有关,但尚不清楚夜间进食的不同特征,包括夜间食欲亢进(EH)和夜间进食(NI),是否会导致初诊为BED的个体出现抑郁。此外,BED患者中常见的睡眠障碍,对NES和抑郁也高度相关。因此,本研究以153例被诊断为BED的患者为样本,考察了包括EH和NI在内的进食障碍、包括初始失眠(即入睡困难)和夜间觉醒在内的睡眠障碍与抑郁之间的关系。初始失眠、夜间觉醒和EH与抑郁显著相关;NI则不然。分层线性回归结果显示,除了整体饮食失调病理因素外,初始失眠和夜间觉醒而非EH对抑郁有显著影响。总体而言,我们的研究结果表明,在进食已受到很大干扰的BED患者中,EH和NI可能不会增加抑郁风险。相比之下,睡眠紊乱似乎确实会带来抑郁风险,这表明在寻求治疗的BED患者中,除了评估饮食模式外,仔细评估睡眠模式也必不可少。

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