Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden.
Aging Research Center, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Solna, Sweden; Stockholm Gerontology Research Center, Stockholm, Sweden.
J Am Med Dir Assoc. 2024 Nov;25(11):105225. doi: 10.1016/j.jamda.2024.105225. Epub 2024 Aug 24.
This study aims to investigate the relationship between frailty and avoidable hospitalization risk, and the moderating role of sociodemographic, clinical, and care-related factors.
Longitudinal population-based cohort study.
A total of 3168 community-dwelling individuals, aged ≥60 years, from the Swedish National study on Aging and Care in Kungsholmen (SNAC-K).
We operationalized physical frailty using baseline SNAC-K data (2001-2004). In line with the Swedish Board of Health and Welfare and Association of Local Authorities and Regions, avoidable hospitalizations were considered those that could have been prevented through proper and timely outpatient care and identified through the Swedish National Patient Register. Participants were followed from baseline until first avoidable hospitalization, death, drop out, institutionalization, or maximum 12 (median 7.6) years. The association between frailty and avoidable hospitalization was explored through flexible parametric survival models, with stratified analyses to investigate age, gender, education, civil status, multimorbidity, cognitive status, and informal and formal care as potential modifiers.
The adjusted 12-year cumulative incidence of avoidable hospitalization was significantly higher for frail persons (cumulative incidence 33.2%, 95% CI 28.9%-38.1%) than for prefrail (cumulative incidence 26.6%, 95% CI 24.5%-29.0%) and nonfrail (cumulative incidence 25.2%, 95% CI 22.5%-28.3%) individuals. In addition, prefrailty [hazard ratio (HR) 1.21, 95% CI 1.00-1.45] and frailty (HR 1.91, 95% CI 1.47-2.50) were associated with increased avoidable hospitalization hazards. Furthermore, the association between frailty and avoidable hospitalization was stronger in older adults aged <78 years (HR 3.12, 95% CI 1.99-4.91) and those with relatively fewer chronic diseases (HR 3.88, 95% CI 1.95-7.72), whereas provision of formal social care (HR 1.15, 95% CI 0.77-1.72) seemed to act as a buffer.
Our results indicate that older community-dwelling adults with prefrailty and frailty are at increased risk of experiencing avoidable hospitalizations, highlighting a need for better care of these individuals at the outpatient level. Formal social care services and close monitoring of particularly vulnerable subgroups of frail persons may mitigate this risk.
本研究旨在探讨衰弱与可避免住院风险之间的关系,并探讨社会人口学、临床和护理相关因素的调节作用。
纵向基于人群的队列研究。
共有 3168 名年龄≥60 岁的居住在社区的个体,来自瑞典 Kungsholmen 老龄化和护理全国研究(SNAC-K)。
我们使用基线 SNAC-K 数据(2001-2004 年)对身体衰弱进行了操作化。根据瑞典卫生局和地方当局及地区协会的定义,可避免的住院治疗被认为是那些可以通过适当和及时的门诊护理来预防的,并通过瑞典国家患者登记处来确定。参与者从基线开始随访,直到首次发生可避免的住院治疗、死亡、退出、住院或最长 12 年(中位数 7.6 年)。通过灵活参数生存模型探讨了衰弱与可避免住院治疗之间的关联,并进行了分层分析,以探讨年龄、性别、教育、婚姻状况、多种合并症、认知状况以及非正式和正式护理作为潜在的调节剂。
衰弱个体 12 年的累积可避免住院治疗发生率明显高于非衰弱个体(累积发生率 33.2%,95%CI 28.9%-38.1%)和非衰弱个体(累积发生率 26.6%,95%CI 24.5%-29.0%)。此外,衰弱前期(HR 1.21,95%CI 1.00-1.45)和衰弱(HR 1.91,95%CI 1.47-2.50)与可避免住院治疗风险增加相关。此外,在年龄<78 岁的老年人(HR 3.12,95%CI 1.99-4.91)和患有较少慢性病的老年人中(HR 3.88,95%CI 1.95-7.72),衰弱与可避免住院治疗之间的关联更强,而提供正式的社会护理(HR 1.15,95%CI 0.77-1.72)似乎起到了缓冲作用。
我们的研究结果表明,衰弱前期和衰弱的社区居住老年人发生可避免住院治疗的风险增加,这突出表明需要更好地在门诊层面为这些个体提供护理。正式的社会护理服务和对脆弱的衰弱个体亚组进行密切监测可能会降低这种风险。