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量化导乐护理与孕产妇及新生儿结局之间的关联。

Quantifying the association between doula care and maternal and neonatal outcomes.

作者信息

Lemon Lara S, Quinn Beth, Young Melissa, Keith Hannah, Ruscetti Amy, Simhan Hyagriv N

机构信息

Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA; Department of Clinical Analytics, University of Pittsburgh Medical Center, Pittsburgh, PA; Magee-Womens Research Institute, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Department of Obstetrics, Gynecology and Reproductive Sciences, Magee-Womens Hospital, University of Pittsburgh School of Medicine, Pittsburgh, PA.

出版信息

Am J Obstet Gynecol. 2025 Apr;232(4):387.e1-387.e43. doi: 10.1016/j.ajog.2024.08.029. Epub 2024 Aug 24.

Abstract

BACKGROUND

The United States suffers from an increasing rate of severe maternal morbidity, paired with a wide disparity in maternal health by race. Doulas are posited to be a useful resource to increase positive outcomes and to decrease this disparity.

OBJECTIVE

This study aimed to evaluate the association between doula care and a broad range of maternal and neonatal outcomes in various subpopulations.

STUDY DESIGN

This was a retrospective cohort study of deliveries that were recorded from January 2021 to December 2022 at a single institution where they received prenatal care. The exposure was receipt of doula care prenatally and at delivery. We evaluated both the maternal (cesarean delivery, cesarean delivery of nulliparous, term, singleton, vertex infant, vaginal birth after cesarean, gestational hypertension, preeclampsia, postpartum emergency department visit, readmission, and attendance of postpartum office visit) and neonatal (neonatal intensive care unit admission, unexpected complications in term newborns, breastfeeding, preterm delivery, and intrauterine growth restriction) outcomes. Because our institution previously employed targeted outreach by offering doula services to patients at highest risk, we used multiple methods to generate an appropriate comparison population. We conducted a multivariate logistic regression and conditional regressions using propensity scores to model the likelihood of doula care to generate adjusted risk differences associated with doula care. Analyses were repeated in populations stratified by race (White vs Black) and then by payor status (public vs commercial).

RESULTS

Our cohort included 17,831 deliveries; 486 of those received doula care and 17,345 did not. Patients who received doula care were more likely to self-report Black race, be publicly insured, and to live in a more disadvantaged neighborhood. Regardless of the analytical approach, for every 100 patients who received doula care, there were 15 to 34 more vaginal births after cesarean (adjusted risk difference, 15.6; 95% confidence interval, 3.8-27.4; adjusted risk difference, 34.2; 95% confidence interval, 0.046-68.0) and 5 to 6 more patients who attended a postpartum office visit (adjusted risk difference, 5.4; 95% confidence interval, 1.4-9.5; adjusted risk difference, 6.8; 95% confidence interval, 3.7-9.9) when compared with those who did not receive doula services. Infants born to these patients were 20% more like likely to be exclusively breastfed (adjusted risk ratio, 1.22; 95% confidence interval, 1.07-1.38), and doula care was associated with 3 to 4 fewer preterm births (adjusted risk difference, -3.8; 95% confidence interval, -6.1 to -1.5; -4.0; 95% confidence interval, -6.2 to -1.8) for every 100 deliveries that received doula care. Results were consistent regardless of race or insurance. Results were also consistent when doula care was redefined as having at least 3 prenatal encounters with a doula.

CONCLUSION

Doula care was associated with more vaginal births after cesarean delivery, improved attendance of postpartum office visits, improved breastfeeding rates, and fewer preterm deliveries. The effect of doula care was consistent across race and insurance status.

摘要

背景

美国严重孕产妇发病率呈上升趋势,且孕产妇健康状况在种族方面存在巨大差异。分娩导乐被认为是增加积极分娩结局并减少这种差异的有用资源。

目的

本研究旨在评估分娩导乐护理与不同亚人群中广泛的孕产妇和新生儿结局之间的关联。

研究设计

这是一项回顾性队列研究,研究对象为2021年1月至2022年12月在一家提供产前护理的单一机构记录的分娩病例。暴露因素是产前和分娩时接受分娩导乐护理。我们评估了孕产妇结局(剖宫产、初产妇剖宫产、足月单胎头位婴儿剖宫产、剖宫产术后阴道分娩、妊娠期高血压、子痫前期、产后急诊就诊、再入院以及产后门诊就诊情况)和新生儿结局(新生儿重症监护病房收治、足月儿意外并发症、母乳喂养、早产以及胎儿宫内生长受限)。由于我们机构之前通过为高危患者提供分娩导乐服务进行了有针对性的推广,我们使用了多种方法来生成合适的对照人群。我们进行了多因素逻辑回归和使用倾向得分的条件回归,以模拟分娩导乐护理的可能性,从而得出与分娩导乐护理相关的调整后风险差异。分析在按种族(白人对黑人)分层的人群中重复进行,然后按支付方状态(公立对商业)分层。

结果

我们的队列包括了17831例分娩;其中486例接受了分娩导乐护理,17345例未接受。接受分娩导乐护理的患者更有可能自我报告为黑人种族、参加公共保险并且居住在更为贫困的社区。无论采用何种分析方法,每100例接受分娩导乐护理的患者中,剖宫产术后阴道分娩的人数比未接受分娩导乐服务的患者多15至34例(调整后风险差异为15.6;95%置信区间为3.8 - 27.4;调整后风险差异为34.2;95%置信区间为0.046 - 68.0),产后门诊就诊的患者多5至6例(调整后风险差异为5.4;95%置信区间为1.4 - 9.5;调整后风险差异为6.8;95%置信区间为3.7 - 9.9)。这些患者所生婴儿纯母乳喂养的可能性高20%(调整后风险比为1.22;95%置信区间为1.07 - 1.38),并且每100例接受分娩导乐护理的分娩中,分娩导乐护理与早产减少3至4例相关(调整后风险差异为 - 3.8;95%置信区间为 - 6.1至 - 1.5; - 4.0;95%置信区间为 - 6.2至 - 1.8)。无论种族或保险情况如何,结果均一致。当将分娩导乐护理重新定义为与导乐至少进行3次产前接触时,结果也一致。

结论

分娩导乐护理与剖宫产术后阴道分娩增加、产后门诊就诊情况改善、母乳喂养率提高以及早产减少相关。分娩导乐护理的效果在种族和保险状态方面是一致的。

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