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心脏植入式电子设备手术期间的术中胸神经阻滞

Intraoperative pectoral nerve blocks during cardiac implantable electronic device procedures.

作者信息

Markman Timothy M, Lin David, Nazarian Saman, van Niekerk Christoffel J, Mirwais Maiwand, Garg Lohit, Bode Weeranun, Smietana Jeffrey, Sugrue Alan, Patel Neel A, Patel Darshak, Ha Bao, Hyman Matthew C, Riley Michael, Callans David J, Deo Rajat, Yang Ruifang, Schaller Robert D, Kumareswaran Ramanan, Guandalini Gustavo S, Epstein Andrew E, Marchlinski Francis E, Frankel David S

机构信息

Department of Medicine, Division of Cardiovascular Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

Department of Medicine, Division of Cardiovascular Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

出版信息

Heart Rhythm. 2025 May;22(5):1264-1269. doi: 10.1016/j.hrthm.2024.07.124. Epub 2024 Aug 24.

Abstract

BACKGROUND

Cardiac implantable electronic device (CIED) procedures can cause significant postoperative pain. Opioid use for postoperative pain is associated with risk of persistent use. The benefits of pectoral nerve (PECs) blocks have been established for other chest wall surgeries, but adoption in electrophysiology has been limited.

OBJECTIVES

The purpose of this study was to evaluate the efficacy of intraoperative ultrasound-guided PECs blocks performed at the time of CIED procedures by the implanting physician from within the device pocket.

METHODS

Patients undergoing a pectoral CIED procedure at 7 centers from 2022-2023 were included. Patients underwent intraoperative PECs blocks and subcutaneous local anesthetic vs subcutaneous local anesthetic only at the discretion of the operator. Patients were prospectively evaluated for postoperative pain.

RESULTS

Six hundred ten patients (age 67 ± 15 years old; 63% male) were enrolled. and half (n = 305) underwent PECs block. Patients who underwent PECs block were more likely to have a history of chronic pain (32% vs 11%, P <.001). PECs block was associated with lower pain scores in the 4 hours after the procedure (1.5 ± 2.1 vs 4.5 ± 2.5, P <.001). Pain scores were not different after 24 hours (2.8 ± 1.7 vs 3.1 ± 2.2) and 2 weeks (0.9 ± 1.4 vs 0.9 ± 1.2). PECs block patients were less likely to receive inpatient opioids (10% vs 48%, P <.001) and to be discharged with an opioid prescription (15% vs 59%, P <.001). In multivariable linear regression, PECs block (P <.001), age (P = .002), and absence of chronic pain (P = .009) were associated with lower acute postoperative pain.

CONCLUSION

Intraoperative PECs block can reduce postoperative pain and opioid use. This procedure can be readily performed by the implanting physician from within the device pocket.

摘要

背景

心脏植入式电子设备(CIED)手术可导致明显的术后疼痛。使用阿片类药物治疗术后疼痛与持续使用风险相关。胸段神经(PECs)阻滞对其他胸壁手术的益处已得到证实,但在电生理领域的应用有限。

目的

本研究旨在评估在CIED手术时由植入医生在设备囊袋内进行术中超声引导下PECs阻滞的疗效。

方法

纳入2022年至2023年在7个中心接受胸段CIED手术的患者。患者根据操作者的判断接受术中PECs阻滞和皮下局部麻醉或仅接受皮下局部麻醉。对患者进行术后疼痛的前瞻性评估。

结果

共纳入610例患者(年龄67±15岁;63%为男性),其中一半(n = 305)接受了PECs阻滞。接受PECs阻滞的患者更有可能有慢性疼痛病史(32%对11%,P <.001)。PECs阻滞与术后4小时内较低的疼痛评分相关(1.5±2.1对4.5±2.5,P <.001)。24小时(2.8±1.7对3.1±2.2)和2周后(0.9±1.4对0.9±1.2)疼痛评分无差异。接受PECs阻滞的患者接受住院阿片类药物治疗的可能性较小(10%对48%,P <.001),出院时开具阿片类药物处方的可能性也较小(15%对59%,P <.001)。在多变量线性回归中,PECs阻滞(P <.001)、年龄(P =.002)和无慢性疼痛(P =.009)与较低的术后急性疼痛相关。

结论

术中PECs阻滞可减轻术后疼痛并减少阿片类药物的使用。该操作可由植入医生在设备囊袋内轻松完成。

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