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短节段脊髓炎为隐球菌感染的突出表现：一例报告。

Short segment myelitis as a dominant manifestation of cryptococcal infection: a case report.

机构信息

Department of Respiratory and Critical Care Medicine, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710043, China.

Department of Neurology, The First Affiliated Hospital Yulin Hospital of Xi'an Jiao Tong University, Yulin, 719000, China.

出版信息

BMC Infect Dis. 2024 Aug 26;24(1):863. doi: 10.1186/s12879-024-09756-5.

DOI:10.1186/s12879-024-09756-5
PMID:39187777
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346243/
Abstract

Cryptococcal infection of central nervous system commonly involves meningitis or meningoencephalitis, but rarely mimics inflammatory myelitis. We present short segment myelitis as a dominant manifestation caused by Cryptococcus neoformans in a patient with nephrotic syndrome under immunosuppressive therapy. This case report highlights Cryptococcus neoformans as a potential etiological factor for short segment myelitis in immunocompromised hosts.

摘要

中枢神经系统的隐球菌感染通常涉及脑膜炎或脑膜脑炎，但很少模仿炎症性脊髓炎。我们报告了一例肾病综合征患者在免疫抑制治疗下以短节段脊髓炎为主要表现的新型隐球菌感染。本病例报告强调了新型隐球菌在免疫功能低下宿主中是短节段脊髓炎的潜在病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9a3/11346243/e4172a1adbc8/12879_2024_9756_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9a3/11346243/e4172a1adbc8/12879_2024_9756_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f9a3/11346243/e4172a1adbc8/12879_2024_9756_Fig1_HTML.jpg

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本文引用的文献

1
Cryptococcal Disease in Diverse Hosts.不同宿主中的隐球菌病
N Engl J Med. 2024 May 2;390(17):1597-1610. doi: 10.1056/NEJMra2311057.
2
A Rare Presentation of Myositis and Diffuse Alveolar Hemorrhage Associated With Disseminated Cryptococcus neoformans Infection.1例与播散性新型隐球菌感染相关的肌炎和弥漫性肺泡出血的罕见病例报告
Cureus. 2023 Jul 18;15(7):e42062. doi: 10.7759/cureus.42062. eCollection 2023 Jul.
3
Cryptococcal infection causing longitudinal extensive transverse myelitis in an immunocompetent individual: Case report and literature review.
免疫功能正常个体中由隐球菌感染引起的长节段横贯性脊髓炎：病例报告及文献综述
Front Neurol. 2023 Apr 13;14:1171572. doi: 10.3389/fneur.2023.1171572. eCollection 2023.
4
Transverse Myelitis Associated with in an Immunocompetent Patient.一名免疫功能正常患者中与[具体病症]相关的横贯性脊髓炎 。 （你提供的原文“Transverse Myelitis Associated with in an Immunocompetent Patient.”中“associated with”后面缺少具体内容，所以翻译出来不太完整，你可以补充完整后让我继续为你准确翻译。）
Case Rep Infect Dis. 2022 Feb 21;2022:2000246. doi: 10.1155/2022/2000246. eCollection 2022.
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Cryptococcal infection of the colon in a patient without concurrent human immunodeficiency infection: a case report and literature review.患者无合并人类免疫缺陷感染时的结肠隐球菌感染：病例报告及文献复习。
Eur J Clin Microbiol Infect Dis. 2021 Dec;40(12):2623-2626. doi: 10.1007/s10096-021-04268-5. Epub 2021 May 13.
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