San Fernando Medical School, Universidad Nacional Mayor de San Marcos, Lima, Peru.
Department of Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Eur J Clin Microbiol Infect Dis. 2021 Dec;40(12):2623-2626. doi: 10.1007/s10096-021-04268-5. Epub 2021 May 13.
Cryptococcosis is a fungal infection that is rarely reported in patients without human immunodeficiency virus (HIV) infection, especially when the central nervous system (CNS) or pulmonary system is not involved. We report a case of isolated colonic cryptococcosis without disseminated disease in a 64-year-old immunocompetent woman without HIV infection who presented with chronic diarrhea and no episodes of fever or weight loss. The diagnosis was based on histopathology examination. Furthermore, we performed a literature review showing that few reports have been published so far and in the case of colonic cryptococcal infection, the prognosis is favorable among HIV-uninfected patients.
隐球菌病是一种真菌感染，在没有人类免疫缺陷病毒 (HIV) 感染的患者中很少见，尤其是当中枢神经系统 (CNS) 或肺部系统未受影响时。我们报告了一例免疫功能正常的 64 岁女性孤立性结肠隐球菌病的病例，该患者无 HIV 感染，表现为慢性腹泻，无发热或体重减轻病史。诊断基于组织病理学检查。此外，我们进行了文献回顾，结果表明到目前为止发表的报告很少，而且在结肠隐球菌感染的情况下，HIV 阴性患者的预后良好。
