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基于文献计量的心血管疾病外泌体研究全球趋势：可视化分析。

Global Research Trends on Exosome in Cardiovascular Diseases: A Bibliometric-Based Visual Analysis.

机构信息

Department of Anatomy, School of Chinese Integrative Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of China.

出版信息

Vasc Health Risk Manag. 2024 Aug 22;20:377-402. doi: 10.2147/VHRM.S473520. eCollection 2024.

DOI:10.2147/VHRM.S473520
PMID:39188326
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346494/
Abstract

BACKGROUND

Exosomes in cardiovascular diseases (CVDs) have attracted huge attention with substantial value and potential. Our bibliometrics is based on literature from the field of cardiovascular exosomes over the past 30 years, which has been visualized to display the development process, research hotspots, and cutting-edge trends of clinical practices, mechanisms, and management strategies related to psych cardiology.

METHODS

We selected articles and reviews on exosomes in CVDs from the core collection of Web of Science, and generated visual charts by using CiteSpace and VOSviewer software.

RESULTS

Our research included 1613 publications. The number of exosome articles in CVD fluctuates slightly, but overall shows an increasing trend. The main research institutions were Tongji University and Nanjing Medical University. The International Journal of Molecular Sciences has the highest publication volume, while the Journal of Cellular and Molecular Medicine has the highest citation count. Among all the authors, Eduardo Marban ranks first in terms of publication volume and H-index. The most common keywords are exosome, extracellular vesicles, and angiogenesis.

CONCLUSION

This is a bibliometric study on the research hotspots and trends of exosomes in CVD. Exosome research in the field of cardiovascular medicine is on the rise. Some exosome treatment methods may become the focus of future research.

摘要

背景

心血管疾病 (CVD) 中的细胞外囊泡引起了广泛关注，具有巨大的价值和潜力。我们的文献计量学基于过去 30 年心血管细胞外囊泡领域的文献，这些文献被可视化，以展示与心理心脏病学相关的临床实践、机制和管理策略的发展过程、研究热点和前沿趋势。

方法

我们从 Web of Science 的核心集选择了关于 CVD 中细胞外囊泡的文章和综述，并使用 CiteSpace 和 VOSviewer 软件生成可视化图表。

结果

我们的研究包括 1613 篇出版物。CVD 中外泌体文章的数量波动较小，但总体呈上升趋势。主要研究机构是同济大学和南京医科大学。《国际分子科学杂志》的发表量最高，而《细胞与分子医学杂志》的被引次数最高。在所有作者中，Eduardo Marban 的发文量和 H 指数排名第一。最常见的关键词是外泌体、细胞外囊泡和血管生成。

结论

这是一项关于 CVD 中外泌体研究热点和趋势的文献计量学研究。心血管医学领域的外泌体研究正在兴起。一些外泌体治疗方法可能成为未来研究的重点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/6cdd464de6f5/VHRM-20-377-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/a9247a9df77d/VHRM-20-377-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/aaea5f736f9d/VHRM-20-377-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/cc9b1f222ad0/VHRM-20-377-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/5d437ddf4994/VHRM-20-377-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/087877a56cb2/VHRM-20-377-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/7b4cf1616617/VHRM-20-377-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/f7838b28f752/VHRM-20-377-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/6d8354474357/VHRM-20-377-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/abfc94f67807/VHRM-20-377-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/6cdd464de6f5/VHRM-20-377-g0010.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/a9247a9df77d/VHRM-20-377-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/aaea5f736f9d/VHRM-20-377-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/cc9b1f222ad0/VHRM-20-377-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/5d437ddf4994/VHRM-20-377-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/087877a56cb2/VHRM-20-377-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/7b4cf1616617/VHRM-20-377-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/f7838b28f752/VHRM-20-377-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/6d8354474357/VHRM-20-377-g0008.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/abfc94f67807/VHRM-20-377-g0009.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8648/11346494/6cdd464de6f5/VHRM-20-377-g0010.jpg

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In Vivo Fluorescent Labeling of Foam Cell-Derived Extracellular Vesicles as Circulating Biomarkers for In Vitro Detection of Atherosclerosis.
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