Mostafavi Yeganeh-Sadat, Iranmanesh Pedram, Khademi Abbasali, Mehrabi Raheleh, Sheikhshoaei Fatemeh, Mohammadi Masoud
Dental Research Center, School of Dentistry, Golestan University of Medical Sciences, Gorgan, Iran.
Department of Endodontics, Dental Research Center, Dental Research Institute, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
Dent Res J (Isfahan). 2024 Jul 12;21:31. eCollection 2024.
Dental pulp regeneration aims to restore the function and vitality of the dental pulp, which is the soft tissue inside the tooth. Research in this field is effective in trying to improve clinical practices and procedures. This study aimed to analyze the literature related to dental pulp regeneration and to create a documented research perspective for this field.
This bibliometric study analyzes the research outputs of the subject area of dental pulp regeneration indexed in the Web of Science database between 2013 and 2023. SciMAT software was used to visualize and predict the trends in research on the topic.
In general, it has been observed that the stem cell cluster consistently had the highest number of articles across all periods. As we progressed through time, the significance of this cluster continued to grow, eventually becoming a crucial component in the motor theme during the last period. In addition, a significant portion of the studies conducted during different periods focused on identifying suitable materials for scaffold formation. Various materials, including polymers and bioactive glasses, were proposed as viable options for scaffold formation in different periods.
Dental pulp stem cells (DPSCs), scaffold networks, growth factors, and regulatory factors are the three main factors that influence dental pulp regeneration. By analyzing maps and thematic clusters in dental pulp regeneration research, as well as considering indicators such as repetition frequency, centrality, and citation of these clusters, researchers can identify the strengths, weaknesses, and gaps in current research.
牙髓再生旨在恢复牙髓(牙齿内部的软组织)的功能和活力。该领域的研究对于改进临床实践和操作是有效的。本研究旨在分析与牙髓再生相关的文献,并为该领域创建一个有文献记载的研究视角。
这项文献计量学研究分析了2013年至2023年期间被科学引文索引数据库收录的牙髓再生主题领域的研究成果。使用SciMAT软件来可视化和预测该主题的研究趋势。
总体而言,观察到干细胞簇在所有时期的文章数量始终最多。随着时间的推移,该簇的重要性持续增长,最终在最后一个时期成为核心主题的关键组成部分。此外,不同时期进行的大部分研究都集中在确定适合用于支架形成的材料。在不同时期,包括聚合物和生物活性玻璃在内的各种材料被提议作为支架形成的可行选择。
牙髓干细胞(DPSCs)、支架网络、生长因子和调节因子是影响牙髓再生的三个主要因素。通过分析牙髓再生研究中的图谱和主题簇,并考虑这些簇的重复频率、中心性和引用等指标,研究人员可以确定当前研究的优势、劣势和差距。