Razouq Boujemaa, Ibba Mouhsin, Mahdaoui Mohamed, El Ouazzani Meryem, Fenane Hicham, Msougar Yassine
Thoracic Surgery, Mohammed VI University Hospital, Marrakesh, MAR.
Neurology, Mohammed VI University Hospital, Marrakesh, MAR.
Cureus. 2024 Jul 26;16(7):e65479. doi: 10.7759/cureus.65479. eCollection 2024 Jul.
Primary pulmonary Hodgkin's lymphoma (PPHL) is an uncommon condition that accounts for less than 1% of all lymphomas. The clinical and radiological presentation of PPHL is nonspecific. This case report aimed to highlight the misleading presentation of PPHL, which initially manifested as a pulmonary cavitary lesion. The presented case report describes a perplexing presentation of PPHL in a 24-year-old female patient. Initially suspected to have necrotizing pneumonia or pulmonary tuberculosis due to symptoms including cough, hemoptysis, and weight loss, the patient underwent various diagnostic procedures, including bronchoscopy and CT-guided biopsy, which failed to provide a definitive diagnosis. Surgical resection was eventually pursued, leading to the conclusive identification of PPHL. This case highlights the diagnostic challenges associated with PPHL, emphasizing the importance of considering this rare entity in the differential diagnosis of pulmonary nodular or cavitary lesions. Prompt recognition and accurate diagnosis are essential for optimal management and improved patient outcomes. PPHL is an infrequent neoplasm that often presents diagnostic dilemmas. It requires consideration within the appropriate clinical framework to ensure timely diagnosis and intervention.
原发性肺霍奇金淋巴瘤（PPHL）是一种罕见疾病，占所有淋巴瘤的比例不到1%。PPHL的临床和影像学表现不具有特异性。本病例报告旨在强调PPHL具有误导性的表现，其最初表现为肺部空洞性病变。所呈现的病例报告描述了一名24岁女性患者PPHL令人困惑的表现。由于出现咳嗽、咯血和体重减轻等症状，该患者最初被怀疑患有坏死性肺炎或肺结核，接受了包括支气管镜检查和CT引导下活检在内的各种诊断程序，但均未能明确诊断。最终进行了手术切除，从而确诊为PPHL。该病例突出了与PPHL相关的诊断挑战，强调了在肺结节或空洞性病变的鉴别诊断中考虑这一罕见实体的重要性。及时识别和准确诊断对于优化治疗管理和改善患者预后至关重要。PPHL是一种罕见的肿瘤，常常带来诊断难题。需要在适当的临床框架内加以考虑，以确保及时诊断和干预。
