Li Ya-Ping, Su Tian, Xue Xiao-Li, Shi Huan-Ren, Su Zhi-Hui, Li Jun
Department of Vascular, Shijiazhuang Hospital of Traditional Chinese Medicine (Eastern Hospital District), Shijiazhuang 050011, Hebei Province, China.
World J Clin Cases. 2024 Aug 26;12(24):5558-5567. doi: 10.12998/wjcc.v12.i24.5558.
Research on the combined use of ear acupoint embedding beans and warming meridians with cold-dispersing formulas for alleviating resting pain in patients with arteriosclerosis obliterans (ASO) remains limited.
To explore the therapeutic efficacy of auricular point embedding beans combined with Wenjing Sanhan prescription in alleviating resting pain in patients with lower-limb ASO.
A total of 100 patients with ASO experiencing resting pain who were treated at our hospital from January 2022 to January 2023 were enrolled. They were randomly allocated into two groups using a double-blind approach. The control group was treated using a warming meridian with a cold-dispersing formula, while the study group received additional treatment with ear acupoint embedding beans. The clinical efficacy, ankle-brachial artery pressure ratio, hemorheological indicators, and traditional Chinese medicine symptom scores were compared between the two groups.
The clinical efficacy rate in the study group was significantly higher (94.00%) than that in the control group (72.00%, < 0.05). Moreover, the ankle-brachial artery pressure ratio was significantly higher in the study group after treatment ( < 0.05). Hemorheological parameters, including whole blood viscosity, plasma viscosity (1.83 ± 0.11) mPa/s, fibrinogen levels (3.30 ± 0.21) g/L, platelet adhesion rate (49.87% ± 10.51%), and erythrocyte aggregation index (1.79 ± 0) were improved in the study group compared to the control group. In addition, the scores for decreased skin temperature (1.41 ± 0.26), intermittent claudication (1.30 ± 0.20), and resting pain (1.23 ± 0.31) were significantly lower in the study group than those in the control group (all < 0.05). The level of oxidative stress in the study group also exhibited significant improvement ( < 0.05), and the levels of inflammatory factors were considerably lower than those in the control group.
The combination of ear point embedding beans and Wenjing Sanhan prescription demonstrates promising clinical efficacy in alleviating resting pain associated with ASO.
关于耳穴埋豆联合温经散寒方缓解动脉硬化闭塞症（ASO）患者静息痛的研究仍然有限。
探讨耳穴埋豆联合温经散寒方缓解下肢ASO患者静息痛的疗效。
选取2022年1月至2023年1月在我院接受治疗的100例有静息痛的ASO患者。采用双盲法将他们随机分为两组。对照组采用温经散寒方治疗，而研究组在对照组基础上增加耳穴埋豆治疗。比较两组的临床疗效、踝肱动脉压比值、血液流变学指标和中医症状评分。
研究组的临床有效率显著高于对照组（94.00% 比72.00%，P<0.05）。此外，研究组治疗后的踝肱动脉压比值显著更高（P<0.05）。与对照组相比，研究组的血液流变学参数得到改善，包括全血黏度、血浆黏度（1.83±0.11）mPa/s、纤维蛋白原水平（3.30±0.21）g/L、血小板黏附率（49.87%±10.51%）和红细胞聚集指数（1.79±0）。此外，研究组皮肤温度降低（1.41±0.26）、间歇性跛行（1.30±0.20）和静息痛（1.23±0.31）的评分显著低于对照组（均P<0.05）。研究组的氧化应激水平也有显著改善（P<0.05），炎症因子水平明显低于对照组。
耳穴埋豆联合温经散寒方在缓解ASO相关静息痛方面显示出有前景的临床疗效。
