Lueangarun Suparuj, Tempark Therdpong
Department of Aesthetic Medicine, College of Integrative Medicine, Dhurakij Pundit University, Bangkok, Thailand.
Division of Dermatology, DeMed Clinic Center, Bangkok, Thailand.
J Lasers Med Sci. 2024 Jul 27;15:e24. doi: 10.34172/jlms.2024.24. eCollection 2024.
Facial partial unilateral lentiginosis (PUL) is an infrequent skin pigmentation disorder characterized by multiple lentigines. Despite the availability of various treatment modalities, there is no standard treatment for PUL. This study reports a successful treatment of facial PUL in a female patient using a novel 532-nm Nd:YAG fractional picosecond laser (FPL). The patient underwent four treatment sessions at four-week intervals. The treatments were administered using a 9 mm high coverage handpiece micro lens array (MLA), with a fluence of 0.2-0.4 J/cm, a frequency of 2 Hz for 2-3 passes, and approximately 10% overlap. The treatment was well-tolerated by the patient, with significant improvement in pigmentation and no significant side effects observed. The outcomes confirmed the efficacy of the 532-nm Nd:YAG FPL in treating facial PUL. The 532-nm Nd:YAG FPL appears to be an effective and well-tolerated treatment for facial PUL, offering significant improvement in pigmentation without notable side effects.
面部部分单侧雀斑样痣（PUL）是一种罕见的皮肤色素沉着障碍，其特征为多发性雀斑样痣。尽管有多种治疗方式，但PUL尚无标准治疗方法。本研究报告了一名女性患者使用新型532nm掺钕钇铝石榴石皮秒分数激光（FPL）成功治疗面部PUL的案例。该患者每隔四周接受四次治疗。治疗使用9mm高覆盖率手持微透镜阵列（MLA）进行，能量密度为0.2-0.4J/cm，频率为2Hz，进行2-3次扫描，重叠率约为10%。患者对治疗耐受性良好，色素沉着有显著改善，未观察到明显副作用。结果证实了532nm掺钕钇铝石榴石FPL治疗面部PUL的有效性。532nm掺钕钇铝石榴石FPL似乎是一种有效且耐受性良好的面部PUL治疗方法，可显著改善色素沉着且无明显副作用。
