Miyayama Chiharu, Shoji Hiromichi, Murano Yayoi, Ito Kanami, Saita Mizue, Naito Toshio, Fukuda Hiroshi, Shimizu Toshiaki
Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo 113-8421, Japan.
Safety and Health Management Office, Hongo-Ochanomizu Campus, Juntendo University, Tokyo 113-8421, Japan.
Pediatr Rep. 2024 Jul 31;16(3):669-677. doi: 10.3390/pediatric16030056.
Early childhood lays the foundation for many outcomes in later life. Recent studies suggest that early childhood development may contribute to lifestyle-related diseases such as obesity, type 2 diabetes, and cardiovascular disease in adulthood; however, there have been few investigations on this association among adults in Japan. Therefore, we examined the relationship between recent physical measurements in adults who underwent health checkups at our university and their physical measurements at birth and during infancy recorded in the Maternal and Child Health Handbook. The median age and body mass index (BMI) of the participants were 36 years and 20.4 kg/m, respectively. BMI at the time of health checkup in adults did not correlate with physical measurements at birth, but it was found to be associated with BMI at 1.5 (regression coefficient (β) 0.53, < 0.05) and 3 (β 0.7, < 0.01) years of age. In addition, the waist-to-height ratio in adulthood was also associated with BMI at 1.5 (β 0.01, < 0.05) and 3 (β 0.01, < 0.05) years of age. These findings suggest that it is critical to provide appropriate guidance to children with high BMI and their parents during health checkups to prevent lifestyle-related disorders in adulthood.
幼儿期为日后的许多结果奠定了基础。最近的研究表明，幼儿期发育可能会导致成年后出现与生活方式相关的疾病，如肥胖症、2型糖尿病和心血管疾病；然而，在日本成年人中，针对这种关联的调查很少。因此，我们研究了在我校接受健康检查的成年人近期身体测量数据与他们在《母子健康手册》中记录的出生时及婴儿期身体测量数据之间的关系。参与者的年龄中位数和体重指数（BMI）分别为36岁和20.4kg/m²。成年人健康检查时的BMI与出生时的身体测量数据无相关性，但发现其与1.5岁（回归系数（β）0.53，P<0.05）和3岁（β0.7，P<0.01）时的BMI相关。此外，成年后的腰高比也与1.5岁（β0.01，P<0.05）和3岁（β0.01，P<0.05）时的BMI相关。这些发现表明，在健康检查期间，为BMI较高的儿童及其父母提供适当指导对于预防成年后与生活方式相关的疾病至关重要。
