Sağlık Bilimleri Üniversitesi, Bilkent Şehir Hastanesi, Ortopedi ve Travmatoloji Anabilim Dalı, 06700 Çankaya, Ankara, Türkiye.
Jt Dis Relat Surg. 2024 Jul 8;35(3):610-617. doi: 10.52312/jdrs.2024.1761.
The aim of this study was to identify the biomechanical and histopathological changes of ligamentum mucosum (LM) in patients with intact versus ruptured anterior cruciate ligament (ACL).
A total of 67 patients (45 males, 22 females; mean age: 33.2±7.9 years; range, 18 to 45 years) who underwent arthroscopic knee surgery for intraarticular pathologies between July 2022 and January 2023 were prospectively analyzed. The patients with LM were divided into two groups as the ACL intact group (n=31) and ACL ruptured group (n=36). Biomechanical tests and histopathological examinations were performed in all LM patients.
Age and body mass index distributions were similar between the groups (p>0.05). Peak force values of the LM in the ACL ruptured group were significantly higher than the ACL intact group (p=0.037). No significant difference was found between the groups in terms of collagen index (p=0.103) and fibroblast count (p=0.821).
The peak force values of the LM were significantly higher in the ACL ruptured group as compared to the ACL intact group, which is probably due to the adaptation of LM in patients with ACL rupture against increased deforming forces to maintain knee stability.
本研究旨在确定未破裂与破裂前交叉韧带（ACL）患者的黏膜下韧带（LM）的生物力学和组织病理学变化。
2022 年 7 月至 2023 年 1 月期间，前瞻性分析了 67 例（45 名男性，22 名女性；平均年龄：33.2±7.9 岁；18 至 45 岁）因关节内病变而行关节镜膝关节手术的患者。将 LM 患者分为 ACL 完整组（n=31）和 ACL 破裂组（n=36）。对所有 LM 患者进行生物力学测试和组织病理学检查。
两组的年龄和体重指数分布相似（p>0.05）。ACL 破裂组 LM 的峰值力值明显高于 ACL 完整组（p=0.037）。两组的胶原指数（p=0.103）和成纤维细胞计数（p=0.821）无显著差异。
与 ACL 完整组相比，ACL 破裂组的 LM 峰值力值明显更高，这可能是由于 ACL 破裂患者的 LM 适应了增加的变形力，以维持膝关节稳定性。
