A. M. Butlerov Institute of Chemistry, Kazan Federal University, Kremlevskaya str. 18, Kazan 420018, Russia.
Arbuzov Institute of Organic and Physical Chemistry, FRC Kazan Scientific Center, Russian Academy of Sciences, Arbuzov str. 8, Kazan 420088, Russia.
Soft Matter. 2024 Sep 11;20(35):7072-7082. doi: 10.1039/d4sm00764f.
For the first time, dendrimers based on thiacalix[4]arenes bearing imidazolium dendrons on one side and alkyl fragments on another side of the macrocyclic platform and symmetrical dendrimers with four dendrons on both sides were synthesized. Dendrons consist of gallic acid-based branches functionalized with imidazolium and triazolium groups. The physicochemical properties of the dendrimers such as micellar concentration (CMC), size, and solubilization capacity were measured. Novel dendrimers exhibit high binding efficiency with calf thymus DNA (ctDNA) as revealed by fluorescence quenching of the DNA-EtBr complex in the presence of macrocycles. Dendrimers have been used as supports for Pd nanoparticles, which show high catalytic activity for the reduction of nitroaromatic compounds.
首次合成了基于硫杂杯[4]芳烃的树枝状大分子，它们的一侧带有咪唑𬭩树枝，另一侧带有烷基片段，以及两侧都带有四个树枝的对称树枝状大分子。树枝由基于没食子酸的支链组成，支链上带有咪唑𬭩和三唑𬭩基团。测量了树枝状大分子的物理化学性质，如胶束浓度（CMC）、大小和增溶能力。新型树枝状大分子与小牛胸腺 DNA（ctDNA）具有高结合效率，这是通过在存在大环的情况下 DNA-EtBr 配合物的荧光猝灭来揭示的。树枝状大分子已被用作 Pd 纳米粒子的载体，它们对硝基芳烃化合物的还原表现出高催化活性。
