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各种运动干预对脑瘫患者运动功能的影响:系统评价和网络荟萃分析。

Effects of various exercise interventions on motor function in cerebral palsy patients: a systematic review and network meta-analysis.

机构信息

College of Rehabilitation Medicine, Shandong University of Traditional Chinese Medicine, No 4655, University Road, Guyunhu Street, Changqing District, Jinan City, Shandong Province, 250355, China.

出版信息

Neurol Sci. 2024 Dec;45(12):5915-5927. doi: 10.1007/s10072-024-07741-z. Epub 2024 Aug 27.

Abstract

PURPOSE

A network meta-analysis was utilized to compare the rehabilitative effectiveness of different exercise interventions on motor function in cerebral palsy(CP) patients.

METHODS

Computer searches were conducted across 9 databases, including PubMed, Cochrane Library, Scopus, Web of Science, Embase, and others, to identify randomized controlled trials focusing on different exercise interventions aimed at enhancing motor function in CP patients. The search spanned from the inception of the databases to January 31, 2024.

RESULTS

20 articles, encompassing 570 patients and evaluating three types of exercise interventions, were included in the analysis. Results showed that aerobic training, resistance training, and mixed training exhibited superior outcomes compared to the control group, as evidenced by improvements in Gross Motor Function Measure scores, muscle strength, gait speed, and 10-Meter Walk Test scores (P < 0.05). Furthermore, the network meta-analysis revealed that resistance training ranked highest in enhancing gross motor function and gait speed among CP patients, while mixed training was deemed most effective in improving muscle strength and 10-Meter Walk Test scores.

CONCLUSION

Exercise interventions have been shown to significantly improve motor function in CP patients. Among these, resistance training and mixed training stand out for their effectiveness in enhancing walking capabilities. Resistance training is specifically aimed at improving gross motor function, while mixed training focuses on increasing muscle strength.

摘要

目的

本研究采用网络荟萃分析比较了不同运动干预措施对脑瘫(CP)患者运动功能康复效果。

方法

通过计算机检索 PubMed、Cochrane Library、Scopus、Web of Science、Embase 等 9 个数据库,搜集关于不同运动干预措施改善 CP 患者运动功能的随机对照试验,检索时限均从各数据库建库至 2024 年 1 月 31 日。

结果

最终纳入 20 篇文献,共 570 例患者,涉及 3 种运动干预措施。结果显示,与对照组相比,有氧运动、抗阻运动和混合运动均能显著改善 GMFM-88 评分、肌肉力量、步行速度和 10m 步行测试(10-MWT)评分(P < 0.05)。进一步的网络荟萃分析显示,抗阻运动在改善 CP 患者粗大运动功能和步行速度方面效果最佳,混合运动在改善肌肉力量和 10-MWT 评分方面效果最好。

结论

运动干预措施可显著改善 CP 患者的运动功能,其中抗阻运动和混合运动对提高步行能力效果显著。抗阻运动尤其能改善粗大运动功能,混合运动则侧重于增强肌肉力量。

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