Malla Reddy Institute of Pharmaceutical Sciences, Jawaharlal Nehru Technological University, Kompally, Hyderabad, Telangana, India.
Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2024 Aug 28;40:e20240023. doi: 10.62958/j.cjap.2024.023.
The burgeoning field of nanotechnology has ushered in innovative Novel drug delivery systems (NDDS) that enhance the efficacy, safety, and patient compliance of pharmaceutical treatments. This study explores the synthesis and application of silver nanoparticles (AgNPs) using green chemistry approaches, specifically leveraging plant extracts as reducing agents. AgNPs, known for their unique physical and chemical properties, including antimicrobial capabilities, offer significant potential in modern drug delivery. This study investigates the potential of using Allium cepa peel waste for the green synthesis of silver nanoparticles. This study also revealed the resultant formation of silver nanoparticles through microscopy and UV spectroscopy, which were further analyzed by Scanning Electron Microscopy. This green synthesis method not only aligns with environmentally friendly practices but also provides a cost-effective and scalable approach to nanoparticle production. We formulated a hair dye incorporating these AgNPs and evaluated its physicochemical parameters, demonstrating enhanced performance compared to control formulations without nanoparticles. This work underscores the promise of green-synthesized nanoparticles in developing advanced drug delivery systems, offering insights into future applications in anticancer and antimicrobial treatments. Our findings advocate for the broader adoption of sustainable nanotechnology in pharmaceutical sciences, potentially revolutionizing the treatment landscape with safer and more effective therapeutic options.
蓬勃发展的纳米技术领域带来了创新的新型药物输送系统 (NDDS)，提高了药物治疗的疗效、安全性和患者顺应性。本研究探索了使用绿色化学方法合成和应用银纳米粒子 (AgNPs)，特别是利用植物提取物作为还原剂。AgNPs 具有独特的物理和化学性质，包括抗菌能力，在现代药物输送中具有重要的应用潜力。本研究调查了利用洋葱皮废物进行绿色合成银纳米粒子的潜力。本研究还通过显微镜和紫外光谱揭示了银纳米粒子的形成，进一步通过扫描电子显微镜进行了分析。这种绿色合成方法不仅符合环保实践，而且为纳米粒子的生产提供了一种具有成本效益和可扩展性的方法。我们制备了一种含有这些 AgNPs 的染发剂，并评估了其物理化学参数，与不含纳米粒子的对照配方相比，表现出更好的性能。这项工作强调了绿色合成纳米粒子在开发先进药物输送系统中的应用前景，为未来在抗癌和抗菌治疗中的应用提供了思路。我们的研究结果主张在药物科学中更广泛地采用可持续的纳米技术，可能会通过更安全、更有效的治疗选择来彻底改变治疗领域。
