• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

自我用药途径:揭示医学和非医学大麻在慢性疼痛管理中的相互作用的描述性研究。

Self-Medication Paths: A Descriptive Study Unveiling the Interplay Between Medical and Nonmedical Cannabis in Chronic Pain Management.

机构信息

Département des sciences de la santé, Université du Québec en Abitibi-Témiscamingue (UQAT), Rouyn-Noranda.

Department of Anesthesiology, Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal.

出版信息

Clin J Pain. 2024 Nov 1;40(11):635-645. doi: 10.1097/AJP.0000000000001241.

DOI:10.1097/AJP.0000000000001241
PMID:39192773
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11462876/
Abstract

OBJECTIVES

Cannabis is used by one-third of people living with chronic pain to alleviate their symptoms despite warnings from several organizations regarding its efficacy and safety. We currently know little about self-medication practices (use of cannabis for therapeutic purposes without guidance), mainly since the legalization of recreational cannabis in countries such as Canada has expanded the scope of this phenomenon. This study aimed to describe legal cannabis self-medication for pain relief in people living with chronic pain and to explore perceptions of the effectiveness and safety of cannabis.

METHODS

A cross-sectional descriptive study was performed among 73 individuals living with chronic pain and using cannabis (Quebec, Canada). Data collection using telephone interviews occurred in early 2023.

RESULTS

Results indicated that 61.6% of participants reported using cannabis without the guidance of a health care professional (self-medication). Surprisingly, among those, 40.0% held a medical authorization. Overall, 20.6% of study participants were using both medical and legal nonmedical cannabis. Different pathways to self-medication were revealed. Proportion of women versus men participants self-medicating were 58.2% versus 70.6% ( P =0.284). In terms of perceptions, 90.4% of the sample perceived cannabis to be effective for pain management; 72.6% estimated that it posed no or minimal health risk.

DISCUSSION

Cannabis research is often organized around medical versus nonmedical cannabis but in the real-world, those 2 vessels are connected. Interested parties, including researchers, health care professionals, and funding agencies, need to consider this. Patients using cannabis feel confident in the safety of cannabis, and many of them self-medicate, which calls for action.

摘要

目的

尽管有几个组织警告大麻的疗效和安全性,但仍有三分之一的慢性疼痛患者使用大麻来缓解症状。我们目前对自我用药(未经指导使用大麻用于治疗目的)的做法知之甚少,主要是因为加拿大等国家娱乐用大麻合法化扩大了这种现象的范围。本研究旨在描述慢性疼痛患者为缓解疼痛而合法使用大麻,并探讨对大麻疗效和安全性的看法。

方法

2023 年初,在魁北克省(加拿大)使用大麻的 73 名慢性疼痛患者中进行了一项横断面描述性研究。通过电话访谈进行数据收集。

结果

结果表明,61.6%的参与者报告在没有医疗保健专业人员指导的情况下使用大麻(自我用药)。令人惊讶的是,其中 40.0%的人持有医疗授权。总体而言,20.6%的研究参与者同时使用医用和合法非医用大麻。揭示了不同的自我用药途径。自我用药的女性参与者与男性参与者的比例分别为 58.2%和 70.6%(P=0.284)。就看法而言,90.4%的样本认为大麻对疼痛管理有效;72.6%的人估计它没有或几乎没有健康风险。

讨论

大麻研究通常围绕医用大麻和非医用大麻组织,但在现实世界中,这两者是相互关联的。包括研究人员、医疗保健专业人员和资助机构在内的利益相关者都需要考虑这一点。使用大麻的患者对大麻的安全性有信心,他们中的许多人自我用药,这需要采取行动。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/f212b32c0bbb/ajp-40-635-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/aa86f8b31c08/ajp-40-635-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/a1ec6fa47f57/ajp-40-635-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/f212b32c0bbb/ajp-40-635-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/aa86f8b31c08/ajp-40-635-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/a1ec6fa47f57/ajp-40-635-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f59b/11462876/f212b32c0bbb/ajp-40-635-g003.jpg

相似文献

1
Self-Medication Paths: A Descriptive Study Unveiling the Interplay Between Medical and Nonmedical Cannabis in Chronic Pain Management.自我用药途径:揭示医学和非医学大麻在慢性疼痛管理中的相互作用的描述性研究。
Clin J Pain. 2024 Nov 1;40(11):635-645. doi: 10.1097/AJP.0000000000001241.
2
Declared Rationale for Cannabis Use Before and After Legalization for Nonmedical Use: A Longitudinal Study of Community Adults in Ontario.非医疗用途大麻合法化前后使用大麻的宣称理由:安大略省社区成年人的纵向研究
Cannabis Cannabinoid Res. 2023 Dec;8(6):1133-1139. doi: 10.1089/can.2021.0128. Epub 2022 Mar 23.
3
Understanding cancer survivors' reasons to medicate with cannabis: A qualitative study based on the theory of planned behavior.理解癌症幸存者用药大麻的原因:基于计划行为理论的定性研究。
Cancer Med. 2021 Jan;10(1):396-404. doi: 10.1002/cam4.3536. Epub 2020 Oct 17.
4
Cannabis use for symptom relief in multiple sclerosis: A cross-sectional survey of webinar attendees in the US and Canada.多发性硬化症症状缓解中大麻的使用:对美国和加拿大网络研讨会参与者的横断面调查。
Mult Scler Relat Disord. 2020 Feb;38:101516. doi: 10.1016/j.msard.2019.101516. Epub 2019 Nov 11.
5
Pain Relief as a Motivation for Cannabis Use Among Young Adult Users With and Without Chronic Pain.缓解疼痛作为青年成人群体中慢性疼痛与非慢性疼痛使用者使用大麻的动机。
J Pain. 2019 Aug;20(8):908-916. doi: 10.1016/j.jpain.2019.02.001. Epub 2019 Feb 6.
6
Calling for Openness to the Study of Cannabis Use in Chronic Pelvic Pain.呼吁对慢性盆腔疼痛中的大麻使用研究持开放态度。
J Obstet Gynaecol Can. 2021 May;43(5):611-613. doi: 10.1016/j.jogc.2020.08.021. Epub 2020 Sep 30.
7
Cannabis for the Management of Pain: Assessment of Safety Study (COMPASS).大麻用于疼痛管理:安全性研究评估(COMPASS)。
J Pain. 2015 Dec;16(12):1233-1242. doi: 10.1016/j.jpain.2015.07.014. Epub 2015 Sep 16.
8
Effect of cannabis use in people with chronic non-cancer pain prescribed opioids: findings from a 4-year prospective cohort study.慢性非癌痛患者使用大麻对阿片类药物处方的影响:一项为期 4 年的前瞻性队列研究结果。
Lancet Public Health. 2018 Jul;3(7):e341-e350. doi: 10.1016/S2468-2667(18)30110-5.
9
Frequency of cannabis and illicit opioid use among people who use drugs and report chronic pain: A longitudinal analysis.药物使用者中报告慢性疼痛的人与同时使用大麻和非法阿片类药物的频率:一项纵向分析。
PLoS Med. 2019 Nov 19;16(11):e1002967. doi: 10.1371/journal.pmed.1002967. eCollection 2019 Nov.
10
Experience of migraine, its severity, and perceived efficacy of treatments among cannabis users.大麻使用者的偏头痛体验、严重程度和治疗效果感知。
Complement Ther Med. 2021 Jan;56:102619. doi: 10.1016/j.ctim.2020.102619. Epub 2020 Nov 20.

引用本文的文献

1
Considering Long-Acting Synthetic Cannabidiol for Chronic Pain: A Narrative Review.考虑使用长效合成大麻二酚治疗慢性疼痛:一项叙述性综述。
Cureus. 2025 Apr 1;17(4):e81577. doi: 10.7759/cureus.81577. eCollection 2025 Apr.
2
Perceived Risk of Medical Cannabis and Prescribed Cannabinoids for Chronic Pain: A Cross-Sectional Study Among Quebec Clinicians.医用大麻和处方大麻素治疗慢性疼痛的感知风险:魁北克临床医生的横断面研究
Cannabis. 2024 Dec 12;7(3):120-133. doi: 10.26828/cannabis/2024/000263. eCollection 2024.

本文引用的文献

1
Cannabis Use Reported by Patients Receiving Primary Care in a Large Health System.在大型医疗系统中接受初级保健的患者报告的大麻使用情况。
JAMA Netw Open. 2024 Jun 3;7(6):e2414809. doi: 10.1001/jamanetworkopen.2024.14809.
2
Canadians' use of cannabis for therapeutic purposes since legalization of recreational cannabis: a cross-sectional analysis by medical authorization status.自娱乐用大麻合法化以来,加拿大人出于治疗目的使用大麻的情况:按医疗授权状况进行的横断面分析。
BMC Med. 2024 Apr 8;22(1):150. doi: 10.1186/s12916-024-03370-7.
3
A Systematic Review of the Psychometric Properties of the Patient Health Questionnaire-4 in Clinical and Nonclinical Populations.
患者健康问卷-4 在临床和非临床人群中的心理测量特性的系统评价。
J Acad Consult Liaison Psychiatry. 2024 Mar-Apr;65(2):178-194. doi: 10.1016/j.jaclp.2023.11.685. Epub 2023 Nov 25.
4
Using PROGRESS-plus to identify current approaches to the collection and reporting of equity-relevant data: a scoping review.使用 PROGRESS-plus 识别当前收集和报告与公平相关数据的方法:范围综述。
J Clin Epidemiol. 2023 Nov;163:70-78. doi: 10.1016/j.jclinepi.2023.09.017. Epub 2023 Oct 4.
5
Perceived risk of harm for different methods of cannabis consumption: A brief report.不同大麻吸食方式所致伤害风险感知:简要报告。
Drug Alcohol Depend. 2023 Oct 1;251:110915. doi: 10.1016/j.drugalcdep.2023.110915. Epub 2023 Aug 9.
6
Why a distinct medical stream is necessary to support patients using cannabis for medical purposes.为什么需要一个独特的医学分支来支持将大麻用于医疗目的的患者。
J Cannabis Res. 2023 Jul 4;5(1):25. doi: 10.1186/s42238-023-00195-8.
7
The evolving culture of medical cannabis in Canada for the management of chronic pain.加拿大医用大麻用于慢性疼痛管理的文化演变。
Front Pharmacol. 2023 Apr 7;14:1153584. doi: 10.3389/fphar.2023.1153584. eCollection 2023.
8
Definition of self-medication: a scoping review.自我药疗的定义:一项范围综述
Ther Adv Drug Saf. 2022 Oct 5;13:20420986221127501. doi: 10.1177/20420986221127501. eCollection 2022.
9
Young Adult Cannabis Users' Perceptions of Cannabis Risks and Benefits by Chronic Pain Status.青少年成人类大麻使用者对大麻风险和益处的认知与慢性疼痛状况有关。
Subst Use Misuse. 2022;57(11):1647-1652. doi: 10.1080/10826084.2022.2102186. Epub 2022 Jul 28.
10
U.S. Trends in Registration for Medical Cannabis and Reasons for Use From 2016 to 2020 : An Observational Study.2016 年至 2020 年美国医用大麻登记趋势及使用原因:一项观察性研究。
Ann Intern Med. 2022 Jul;175(7):945-951. doi: 10.7326/M22-0217. Epub 2022 Jun 14.