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大麻使用者的偏头痛体验、严重程度和治疗效果感知。

Experience of migraine, its severity, and perceived efficacy of treatments among cannabis users.

机构信息

Department of Psychology and Neuroscience, University of Colorado, Boulder, CO, USA.

Department of Psychology and Neuroscience, University of Colorado, Boulder, CO, USA; Institute of Cognitive Science, University of Colorado, Boulder, CO, USA.

出版信息

Complement Ther Med. 2021 Jan;56:102619. doi: 10.1016/j.ctim.2020.102619. Epub 2020 Nov 20.

Abstract

OBJECTIVES

As the legal and cultural landscape surrounding cannabis use in the United States continues to evolve, more Americans are turning to cannabis to self-medicate a number of ailments, including migraines. The purpose of the present study was to examine patterns of cannabis use and its associated relief among migraineurs.

DESIGN

Participants were N = 589 adult cannabis users living in states with full legal access. Using a cross-sectional design, participants completed an online survey assessing their cannabis use profiles, migraine experience, and self-reported relief from cannabis and non-cannabis treatments.

RESULTS

161 participants (27.3 %) reported experiencing migraines. 76.4 % of migraineurs (N = 123) endorsed using cannabis to treat their migraines. 69.9 % (N = 86) of migraineurs using cannabis for migraine relief also endorsed using non-cannabis products (e.g., over-the-counter pain medication, triptans) to treat their migraines. Although their subjective health was similar (p = .17), migraineurs who endorsed using cannabis to treat their migraines reported more severe migraines compared to those who did not (p = .02). Migraineurs reported significantly more migraine relief from cannabis compared to non-cannabis products, even after controlling for migraine severity (p = .03). The majority of migraineurs using cannabis to treat their migraines were not medical cardholders (65.0 %), suggesting that these individuals were self-medicating in lieu of physician guidance.

CONCLUSIONS

The present study provides insight into the prevalence of cannabis use for migraine relief in a sample of cannabis users, and suggests that these migraineurs experience a high level of migraine relief from cannabis. Future studies are needed to determine the cannabis forms, potencies, and dosages that are most effective at treating migraine pain.

摘要

目的

随着美国围绕大麻使用的法律和文化环境不断演变,越来越多的美国人开始使用大麻来治疗多种疾病,包括偏头痛。本研究的目的是研究偏头痛患者使用大麻的模式及其相关缓解情况。

设计

参与者为 N = 589 名居住在全面合法使用大麻的州的成年大麻使用者。采用横断面设计,参与者完成了一项在线调查,评估了他们的大麻使用情况、偏头痛经历以及大麻和非大麻治疗的自我报告缓解情况。

结果

161 名参与者(27.3%)报告有偏头痛经历。76.4%(N = 123)的偏头痛患者表示使用大麻来治疗偏头痛。69.9%(N = 86)的偏头痛患者使用大麻缓解偏头痛的同时也使用非大麻产品(例如,非处方止痛药、曲坦类药物)来治疗偏头痛。尽管他们的主观健康状况相似(p =.17),但表示使用大麻治疗偏头痛的偏头痛患者报告的偏头痛更严重(p =.02)。偏头痛患者报告使用大麻治疗偏头痛的缓解效果明显优于非大麻产品,即使在控制偏头痛严重程度后(p =.03)。使用大麻治疗偏头痛的偏头痛患者中,大多数没有医疗卡(65.0%),这表明这些患者是在没有医生指导的情况下自行治疗。

结论

本研究提供了在大麻使用者样本中使用大麻缓解偏头痛的流行情况的见解,并表明这些偏头痛患者从大麻中获得了很高水平的偏头痛缓解。需要进一步研究确定治疗偏头痛疼痛最有效的大麻形式、效力和剂量。

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