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通过牛津膝关节评分评估发展中国家同期双侧全膝关节置换术的早期疗效:一项前瞻性队列研究

Early Outcome of Simultaneous Bilateral Total Knee Arthroplasty Through the Oxford Knee Score in a Developing Country: A Prospective Cohort.

作者信息

Sulaiman Muhammad Ahsan, Ghazni Muhammad Ahmed, Farooq Muhammad Omer, Arshad Khan Muhammad Arbaz, Noor S M Nabeel, Hashmi Pervaiz

机构信息

Orthopedics, Aga Khan University Hospital, Karachi, PAK.

出版信息

Cureus. 2024 Jul 28;16(7):e65563. doi: 10.7759/cureus.65563. eCollection 2024 Jul.

DOI:10.7759/cureus.65563
PMID:39192913
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11348276/
Abstract

Introduction The most common degenerative joint disease in adults is osteoarthritis. The gold standard treatment option for this aging society with greater functional demands is total knee arthroplasty. The Oxford Knee Score (OKS) assesses factors such as stiffness, pain, function, satisfaction, and quality of life, allowing you to quantify treatment success after surgery. According to published research, there isn't a perfect postoperative timepoint to use the OKS to obtain TKA outcomes. Therefore, at the time of evaluation, the OKS should reflect the best possible outcome for the patient group. This study was conducted to see the OKS in patients who underwent simultaneous bilateral knee replacement at six weeks and six months postoperatively and to see if there was a clinically significant difference in the mean OKS. Methods This prospective cross-sectional study was conducted at the Section of Orthopedic Surgery at Aga Khan University Hospital, a tertiary care center in Karachi, Pakistan. Patients who underwent simultaneous bilateral total knee replacement from October 2023 till December 2023 were included; exclusion criteria included patients who had a recent knee infection and extensor mechanism disruption. OKS was calculated at six weeks and six months postoperatively. Results The total number of patients included in the study was 49 with a mean age of 61.9 +/- 6.1. There were 42 (85.7%) females and 7 (14.3%) males. The mean BMI of our patients was 33.3 +/- 3.8. The radiographic Kellgren Lawrence Grading (KLG) was used and 38 (77.6%) patients were placed in Grade IV KLG, and 11 (22.4%) were placed in Grade III KLG. The mean OKS preoperatively was 12.6 +/- 3.5. At six weeks, the OKS showed improvement, with the mean being 20.6 +/- 3.0. At six months postoperatively, there was a significant improvement in the OKS, with the mean now being 42.7 +/- 2.4. At six weeks post-surgery, the mean improvement in the OKS score was 7.9 +/- 2.71, whereas at six months post-surgery, the mean improvement in the OKS score was 30.1 +/- 3.6. This difference was significant (-value=0.03). Conclusion Our study showed a clinically significant difference between the mean OKS at the six-week and six-month timeline, with a significant increase in the mean improvement OKS score at six months. OKS should be utilized six months postoperatively to assess the outcome of simultaneous bilateral knee arthroplasty patients.

摘要

引言 成人中最常见的退行性关节疾病是骨关节炎。对于这个功能需求更高的老龄化社会来说,全膝关节置换术是金标准治疗选择。牛津膝关节评分(OKS)评估诸如僵硬、疼痛、功能、满意度和生活质量等因素,使你能够量化手术后的治疗效果。根据已发表的研究,没有一个完美的术后时间点可用于使用OKS来获得全膝关节置换术的结果。因此,在评估时,OKS应反映患者群体可能达到的最佳结果。本研究旨在观察在术后六周和六个月接受同期双侧膝关节置换术的患者的OKS情况,并观察平均OKS是否存在临床显著差异。

方法 这项前瞻性横断面研究在巴基斯坦卡拉奇的三级医疗中心阿迦汗大学医院骨科进行。纳入2023年10月至2023年12月期间接受同期双侧全膝关节置换术的患者;排除标准包括近期有膝关节感染和伸肌机制破坏的患者。在术后六周和六个月计算OKS。

结果 本研究纳入的患者总数为49例,平均年龄为61.9±6.1岁。女性42例(85.7%),男性7例(14.3%)。我们患者的平均体重指数为33.3±3.8。使用放射学Kellgren Lawrence分级(KLG),38例(77.6%)患者被评为IV级KLG,11例(22.4%)被评为III级KLG。术前平均OKS为12.6±3.5。在六周时,OKS显示出改善,平均值为20.6±3.0。术后六个月,OKS有显著改善,平均值现为42.7±2.4。术后六周时,OKS评分的平均改善为7.9±2.71,而术后六个月时,OKS评分的平均改善为30.1±3.6。这种差异具有显著性(P值=0.03)。

结论 我们的研究显示,在六周和六个月时间点的平均OKS之间存在临床显著差异,六个月时OKS评分的平均改善显著增加。应在术后六个月使用OKS来评估同期双侧膝关节置换术患者的结果。

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Early Outcome of Simultaneous Bilateral Total Knee Arthroplasty Through the Oxford Knee Score in a Developing Country: A Prospective Cohort.通过牛津膝关节评分评估发展中国家同期双侧全膝关节置换术的早期疗效:一项前瞻性队列研究
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Patients in high- and low-revision hospitals have similar outcomes after primary knee arthroplasty: 1-year postoperative results from the Danish prospective multicenter cohort study, SPARK.高、低修复医院的初次膝关节置换术后患者的结局相似:丹麦前瞻性多中心队列研究 SPARK 的 1 年术后结果。
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本文引用的文献

1
Similar Recovery Rate for Patients Aged between 50 and 89 Years That Go Home on the Surgery Day and Self-Administer Their Rehabilitation after Kinematically Aligned Total Knee Arthroplasty.在运动学对齐全膝关节置换术后于手术当天回家并自行进行康复训练的50至89岁患者的恢复率相似。
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Gender and Sex Are Key Determinants in Osteoarthritis Not Only Confounding Variables. A Systematic Review of Clinical Data.性别和性是骨关节炎的关键决定因素,而非仅仅是混杂变量。临床数据的系统评价
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One-year Oxford knee scores should be used in preference to 6-month scores when assessing the outcome of total knee arthroplasty.在评估全膝关节置换术的结果时,应优先使用一年期牛津膝关节评分而非六个月评分。
Knee Surg Relat Res. 2020 Aug 28;32(1):43. doi: 10.1186/s43019-020-00060-5.
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There is no clinically important difference in the Oxford knee scores between one and two years after total knee arthroplasty: The one-year score could be used as the benchmark timepoint to assess outcome.全膝关节置换术后1年和2年的牛津膝关节评分在临床上没有显著差异:1年评分可作为评估结果的基准时间点。
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The clinical and cost-effectiveness of total versus partial knee replacement in patients with medial compartment osteoarthritis (TOPKAT): 5-year outcomes of a randomised controlled trial.全膝关节置换与部分膝关节置换治疗内侧间室骨关节炎患者的临床效果和成本效益(TOPKAT):一项随机对照试验的 5 年结果。
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JB JS Open Access. 2018 Mar 12;3(1):e0029. doi: 10.2106/JBJS.OA.17.00029. eCollection 2018 Mar 29.
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Cost-effectiveness of unicompartmental compared with total knee replacement: a population-based study using data from the National Joint Registry for England and Wales.单髁膝关节置换与全膝关节置换的成本效益:一项基于人群的研究,使用来自英格兰和威尔士国家关节登记处的数据。
BMJ Open. 2018 Apr 29;8(4):e020977. doi: 10.1136/bmjopen-2017-020977.
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Treatment Success Following Joint Arthroplasty: Defining Thresholds for the Oxford Hip and Knee Scores.关节置换术后的治疗成功:定义牛津髋关节和膝关节评分的阈值。
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Total knee arthroplasty: improving outcomes with a multidisciplinary approach.全膝关节置换术:采用多学科方法改善治疗效果
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