Gupta Aditya K, Shemer Avner, Economopoulos Vasiliki, Talukder Mesbah
Division of Dermatology, Department of Medicine, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 3H2, Canada.
Mediprobe Research Inc., London, ON N5X 2P1, Canada.
J Fungi (Basel). 2024 Aug 15;10(8):577. doi: 10.3390/jof10080577.
Diabetes Mellitus (DM) is a significant global concern. Many diabetic patients will experience complications due to angiopathy, neuropathy, and immune dysfunction, namely diabetic foot ulcers (DFU) and diabetic foot infections (DFI), which can result in lower limb amputation and potentially death. The prevalence of common superficial fungal infections, such as tinea pedis and onychomycosis, can directly increase a diabetic patient's risk of developing both DFU and DFI. In this review article, we discuss the etiology of diabetic foot complications as well as considerations for both screening and management. We also discuss the role of the dermatologist within a multidisciplinary care team in prescribing and managing treatments for tinea pedis and onychomycosis infections within this patient population. We believe that reducing the burden of these fungal infections in the context of the diabetic foot will help reduce DFU and DFI complications and their associated morbidity and mortality.
糖尿病（DM）是一个重大的全球关注问题。许多糖尿病患者会因血管病变、神经病变和免疫功能障碍而出现并发症，即糖尿病足溃疡（DFU）和糖尿病足感染（DFI），这可能导致下肢截肢甚至死亡。常见的浅表真菌感染，如足癣和甲癣的患病率会直接增加糖尿病患者发生DFU和DFI的风险。在这篇综述文章中，我们讨论了糖尿病足并发症的病因以及筛查和管理方面的注意事项。我们还讨论了皮肤科医生在多学科护理团队中为该患者群体开具和管理足癣和甲癣感染治疗方案的作用。我们认为，在糖尿病足的背景下减轻这些真菌感染的负担将有助于减少DFU和DFI并发症及其相关的发病率和死亡率。
