Muñoz-Antoli Carla, Pavón Aleyda, Comas Jacklyn, Toledo Rafael, Esteban José Guillermo
Área Parasitología, Departamento Farmacia y Tecnología Farmacéutica y Parasitología, Facultad Farmacia y Ciencias de la Alimentación, Universidad Valencia, Burjassot, 46100 Valencia, Spain.
Centro de Investigaciones y Estudios de la Salud, Universidad Nacional Autónoma de Nicaragua, Managua 14172, Nicaragua.
Trop Med Infect Dis. 2024 Jul 30;9(8):171. doi: 10.3390/tropicalmed9080171.
A cross-sectional study was conducted in Masaya (Nicaragua) to estimate the prevalence of intestinal parasite (IP) infections in patients with non-communicable diseases (NCDs) and to determine the associations between the types of NCDs and patients' epidemiological characteristics of infection.
A total of 157 preserved faecal samples were examined (direct wet mount, formalin/ethyl acetate concentration and modified Ziehl-Neelsen technique). Microscopically positive faecal sample identification was completed by conducting a molecular study.
The total prevalence of IP was 52% in NCD patients. Diabetic patients presented an IP prevalence of 42%. presented the highest prevalence (42%). A molecular analysis of (prevalence of 1.3%) revealed 100% of sub-assemblage BIII and the complex (5%) was identified as . ST1 appeared in 44% of those suffering from diabetes and ST3 in 66% of those suffering from hypertension, while ST2 only appeared in those suffering with several NCDs simultaneously. In diabetic patients, the risk of infection is associated with having pets ( = 0.021) and land-floor houses. The risk of infection appears to be statistically related ( = 0.019) in those with several NCDs having received a previous helminthic deworming treatment.
Coordinated public health activities for IP and NCD screening and diagnosis are crucial to their successful control programmes.
在尼加拉瓜马萨亚进行了一项横断面研究，以估计非传染性疾病（NCDs）患者肠道寄生虫（IP）感染的患病率，并确定非传染性疾病类型与患者感染的流行病学特征之间的关联。
共检查了157份保存的粪便样本（直接湿涂片、福尔马林/乙酸乙酯浓缩法和改良齐-尼氏技术）。通过分子研究完成显微镜下阳性粪便样本的鉴定。
非传染性疾病患者中肠道寄生虫的总患病率为52%。糖尿病患者的肠道寄生虫患病率为42%。患病率最高（42%）。对（患病率为1.3%）的分子分析显示100%为亚组合BIII，并且鉴定出复合体（5%）为。ST1出现在44%的糖尿病患者中，ST3出现在66%的高血压患者中，而ST2仅出现在同时患有几种非传染性疾病的患者中。在糖尿病患者中，感染风险与养宠物（P = 0.021）和地面房屋有关。在接受过先前驱虫治疗的几种非传染性疾病患者中，感染风险似乎具有统计学相关性（P = 0.019）。
针对肠道寄生虫和非传染性疾病筛查与诊断的协调公共卫生活动对其成功的控制计划至关重要。
