尼加拉瓜马萨亚慢性非传染性疾病患者肠道寄生虫的存在情况

Presence of Intestinal Parasites in Patients with Chronic Non-Communicable Diseases in Masaya (Nicaragua).

作者信息

Muñoz-Antoli Carla, Pavón Aleyda, Comas Jacklyn, Toledo Rafael, Esteban José Guillermo

机构信息

Área Parasitología, Departamento Farmacia y Tecnología Farmacéutica y Parasitología, Facultad Farmacia y Ciencias de la Alimentación, Universidad Valencia, Burjassot, 46100 Valencia, Spain.

Centro de Investigaciones y Estudios de la Salud, Universidad Nacional Autónoma de Nicaragua, Managua 14172, Nicaragua.

出版信息

Trop Med Infect Dis. 2024 Jul 30;9(8):171. doi: 10.3390/tropicalmed9080171.

DOI:10.3390/tropicalmed9080171

PMID:39195609

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11359410/

Abstract

AIMS

A cross-sectional study was conducted in Masaya (Nicaragua) to estimate the prevalence of intestinal parasite (IP) infections in patients with non-communicable diseases (NCDs) and to determine the associations between the types of NCDs and patients' epidemiological characteristics of infection.

METHODS

A total of 157 preserved faecal samples were examined (direct wet mount, formalin/ethyl acetate concentration and modified Ziehl-Neelsen technique). Microscopically positive faecal sample identification was completed by conducting a molecular study.

RESULTS

The total prevalence of IP was 52% in NCD patients. Diabetic patients presented an IP prevalence of 42%. presented the highest prevalence (42%). A molecular analysis of (prevalence of 1.3%) revealed 100% of sub-assemblage BIII and the complex (5%) was identified as . ST1 appeared in 44% of those suffering from diabetes and ST3 in 66% of those suffering from hypertension, while ST2 only appeared in those suffering with several NCDs simultaneously. In diabetic patients, the risk of infection is associated with having pets ( = 0.021) and land-floor houses. The risk of infection appears to be statistically related ( = 0.019) in those with several NCDs having received a previous helminthic deworming treatment.

CONCLUSIONS

Coordinated public health activities for IP and NCD screening and diagnosis are crucial to their successful control programmes.

摘要

目的

在尼加拉瓜马萨亚进行了一项横断面研究，以估计非传染性疾病（NCDs）患者肠道寄生虫（IP）感染的患病率，并确定非传染性疾病类型与患者感染的流行病学特征之间的关联。

方法

共检查了157份保存的粪便样本（直接湿涂片、福尔马林/乙酸乙酯浓缩法和改良齐-尼氏技术）。通过分子研究完成显微镜下阳性粪便样本的鉴定。

结果

非传染性疾病患者中肠道寄生虫的总患病率为52%。糖尿病患者的肠道寄生虫患病率为42%。患病率最高（42%）。对（患病率为1.3%）的分子分析显示100%为亚组合BIII，并且鉴定出复合体（5%）为。ST1出现在44%的糖尿病患者中，ST3出现在66%的高血压患者中，而ST2仅出现在同时患有几种非传染性疾病的患者中。在糖尿病患者中，感染风险与养宠物（P = 0.021）和地面房屋有关。在接受过先前驱虫治疗的几种非传染性疾病患者中，感染风险似乎具有统计学相关性（P = 0.019）。