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MAC for halothane, enflurane, and isoflurane in the New Zealand white rabbit: and a test for the validity of MAC determinations.

作者信息

Drummond J C

出版信息

Anesthesiology. 1985 Mar;62(3):336-8. doi: 10.1097/00000542-198503000-00020.

DOI:10.1097/00000542-198503000-00020
PMID:3919617
Abstract

MAC determinations for halothane, enflurane, and isoflurane were performed in New Zealand white rabbits (n = 8, approximate age 6 months). The MAC values (+/-SD) were as follows: halothane 1.39 +/- 0.23%, enflurane 2.86 +/- 0.18%, and isoflurane 2.05 +/- 0.18%. Comparison of these results with published MAC values for other species suggests that the ratio of the potencies for any pairing of these three agents is constant from species to species. This observation provides a means for assessing the validity of preexisting or newly determined MAC values.

摘要

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