Marlar Audrey I, Knabe Bradley K, Taghikhan Yasamin, Applegate Richard L, Fleming Neal W
Davis School of Medicine, University of California, Sacramento, CA, USA.
Department of Anesthesiology, Loma Linda University, Loma Linda, CA, USA.
J Clin Monit Comput. 2025 Feb;39(1):119-125. doi: 10.1007/s10877-024-01211-9. Epub 2024 Aug 28.
Pulse oximetry (SpO) is a critical monitor for assessing oxygenation status and guiding therapy in critically ill patients. Race has been identified as a potential source of SpO error, with consequent bias and inequities in healthcare. This study was designed to evaluate the incidence of occult hypoxemia and accuracy of pulse oximetry associated with the Massey-Martin scale and characterize the relationship between Massey scores and self-identified race. This retrospective single institute study utilized the Massey-Martin scale as a quantitative assessment of skin pigmentation. These values were recorded peri-operatively in patients enrolled in unrelated clinical trials. The electronic medical record was utilized to obtain demographics, arterial blood gas values, and time matched SpO values for each PaO ≤ 125 mmHg recorded throughout their hospitalizations. Differences between SaO and SpO were compared as a function of both Massey score and self-reported race. 4030 paired SaO-SpO values were available from 579 patients. The average error (SaO-SpO) ± SD was 0.23 ± 2.6%. Statistically significant differences were observed within Massey scores and among races, with average errors that ranged from - 0.39 ± 2.3 to 0.53 ± 2.5 and - 0.55 ± 2.1 to 0.37 ± 2.7, respectively. Skin color varied widely within each self-identified race category. There was no clinically significant association between error rates and Massey-Martin scale grades and no clinically significant difference in accuracy observed between self-reported Black and White patients. In addition, self-reported race is not an appropriate surrogate for skin color.
脉搏血氧饱和度测定法(SpO)是评估危重症患者氧合状态和指导治疗的关键监测手段。种族已被确定为SpO误差的一个潜在来源,进而导致医疗保健中的偏差和不平等。本研究旨在评估隐匿性低氧血症的发生率以及与梅西-马丁量表相关的脉搏血氧饱和度测定法的准确性,并描述梅西评分与自我认定种族之间的关系。这项回顾性单机构研究采用梅西-马丁量表作为皮肤色素沉着的定量评估方法。这些数值在参与不相关临床试验的患者手术期间进行记录。利用电子病历获取患者的人口统计学信息、动脉血气值以及整个住院期间记录的每个动脉血氧分压(PaO)≤125 mmHg时的时间匹配SpO值。将氧饱和度(SaO)和SpO之间的差异作为梅西评分和自我报告种族的函数进行比较。从579名患者中获得了4030对SaO-SpO值。平均误差(SaO-SpO)±标准差为0.23±2.6%。在梅西评分和不同种族之间观察到了统计学上的显著差异,平均误差分别为-0.39±2.3至0.53±2.5以及-0.55±2.1至0.37±2.7。在每个自我认定的种族类别中,肤色差异很大。错误率与梅西-马丁量表等级之间没有临床显著关联,自我报告的黑人和白人患者在准确性方面也没有临床显著差异。此外,自我报告的种族并不是肤色的合适替代指标。