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童年期虐待与饮食失调风险:观察性研究的荟萃分析

Childhood maltreatment and the risk of eating disorders: a meta-analysis of observational studies.

作者信息

Amiri Sohrab, Sabzehparvar Mahtab

机构信息

Medicine, Quran and Hadith Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Department of General psychology, Faculty of Literature, humanities and social sciences, Science and Research branch, Islamic Azad University, Tehran, Iran.

出版信息

Neuropsychiatr. 2025 Mar;39(1):36-46. doi: 10.1007/s40211-024-00505-3. Epub 2024 Aug 28.

Abstract

OBJECTIVE

The purpose of this systematic review and meta-analysis is to examine the relationship between childhood maltreatment as a variable of exposure and eating disorders as an outcome.

METHODS

PubMed, Web of Science, and Google Scholar were searched to find manuscripts related to the current research. The search was conducted up until October 2023 and limited to the English language. An odds ratio (OR) based on the random effects method was used to combine studies. One subgroup analysis was performed based on the type of eating disorder and another based on the type of childhood maltreatment.

RESULTS

Thirty eligible studies were recognized for this research. Childhood maltreatment was associated with a rate of eating disorders of more than double: OR 2.37 with 95% confidence interval (CI) 1.84-3.06 (P < 0.001; I = 92.6%). Childhood maltreatment was associated with anorexia nervosa (OR 1.89, 95% CI 1.47-2.42; Z = 5.03; P < 0.001; I = 0%), bulimia nervosa (OR 2.64, 95% CI 1.34-5.17; Z = 2.82; P = 0.005; I = 93.1%), and binge eating disorder (OR 1.76, 95% CI 1.38-2.26; Z = 4.52; P < 0.001; I = 80.2%).

CONCLUSION

The findings of this research showed that childhood maltreatment significantly increases the risk of eating disorders. Therefore, in understanding the mechanisms related to eating disorders, it is necessary to pay attention to the issue of the childhood living environment and the traumatic experiences of that time.

摘要

目的

本系统评价和荟萃分析旨在研究作为暴露变量的童年期虐待与作为结果的饮食失调之间的关系。

方法

检索了PubMed、科学网和谷歌学术,以查找与当前研究相关的手稿。检索截至2023年10月,且仅限于英文文献。采用基于随机效应方法的比值比(OR)来合并研究。基于饮食失调类型进行了一项亚组分析,另一项基于童年期虐待类型进行。

结果

本研究识别出30项符合条件的研究。童年期虐待与饮食失调发生率的关联超过两倍:OR为2.37,95%置信区间(CI)为1.84 - 3.06(P < 0.001;I = 92.6%)。童年期虐待与神经性厌食症(OR 1.89,95% CI 1.47 - 2.42;Z = 5.03;P < 0.001;I = 0%)、神经性贪食症(OR 2.64,95% CI 1.34 - 5.17;Z = 2.82;P = 0.005;I = 93.1%)和暴饮暴食症(OR 1.76,95% CI 1.38 - 2.26;Z = 4.52;P < 0.001;I = 80.2%)相关。

结论

本研究结果表明,童年期虐待显著增加了饮食失调的风险。因此,在理解与饮食失调相关的机制时,有必要关注童年生活环境问题以及当时的创伤经历。

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